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Cross-Education and Mirror Therapy for Upper Limb in Post-Stroke Patients

Combining Cross-Education and Mirror Therapy for Upper Limb Rehabilitation in Post-Stroke Patients: A Randomized Controlled Trial

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05920031
Enrollment
100
Registered
2023-06-27
Start date
2023-06-28
Completion date
2024-10-20
Last updated
2023-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Brief summary

This randomized controlled trial will investigate the potential synergistic effects of combining cross-education training with mirror therapy on strength and motor function in the more affected upper limb of post-stroke patients.

Interventions

Participants will perform resistance exercises at 60% of their 1 repetition maximum (1RM) with the less affected limb. The intervention will be performed three times per week for 8 weeks. Each session will consist of three sets of 15 repetitions of bicep curls, tricep extensions, and wrist flexion/extension exercises with a 1-minute rest period between sets. The exercises will be performed in a seated position, with the participant's forearm resting on a table and the therapist providing manual resistance. The therapist will be positioned in front of the participant.

OTHERMirror therapy

Participants will perform bilateral upper limb movements while observing the reflection of the less affected limb in a mirror. The intervention will be performed three times per week for 8 weeks. Each session will consist of 10 minutes of mirror therapy, with the participant seated in front of a mirror. The participant will perform various upper limb movements, such as reaching and grasping, while observing the mirror reflection of the less affected limb. The therapist will be positioned beside the participant, providing verbal cues and feedback as necessary.

OTHERConventional Physical Therapy

articipants will receive conventional rehabilitation for post-stroke upper limb motor impairments, which may include exercises such as range of motion, stretching, and strengthening of the affected limb, as well as other therapies such as electrical stimulation or constraint-induced movement therapy. The intervention will be individualized for each participant and will be performed three times per week for 8 weeks. The frequency, duration, and intensity of the exercises will be gradually increased over the course of the intervention, based on the participant's progress. The exercises may be performed in a seated or standing position, depending on the participant's ability and preference. The therapist will be positioned in front of or beside the participant, providing verbal cues and feedback as necessary.

Sponsors

Ahram Canadian University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
30 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Post-stroke patients with upper limb motor impairments * Aged 30 years to 60 years old * At least 3 months post-stroke * Able to participate in the intervention

Exclusion criteria

* Severe cognitive impairments * Visual impairments * Any contraindications to the intervention

Design outcomes

Primary

MeasureTime frameDescription
Changes in Upper limb strengthChanges in Upper limb strength at baseline, 8 weeks, 16 weeksUpper limb strength (measured by hand-held dynamometry)
Changes in motor functionChanges in motor function at baseline, 8 weeks, 16 weeksmotor function (measured by Fugl-Meyer Assessment)

Secondary

MeasureTime frameDescription
Changes in Quality of lifeChanges in Quality of life at baseline, 8 weeks, 16 weeksQuality of life (measured by Stroke Impact Scale)

Countries

Egypt

Contacts

Primary ContactMohamed M ElMeligie, Ph.d
mohamed.elmeligie@acu.edu.eg+201064442032

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026