cGVHD
Conditions
Keywords
chronic graft versus host disease, cGVHD, MA-GVHD-401, THRIVE, GVHD, chronic GVHD, allogenic stem cell transplant (alloSCT)
Brief summary
The purpose of this prospective observational study is to collect data from participants who have recently had an allogenic Stem Cell Transplant(alloSCT) and are at risk of Chronic Graft Versus Host Disease(cGVHD)
Interventions
OTHERNon-Interventional
This is an observational study
Sponsors
Incyte Corporation
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥ 18 years inclusive at the time of signing the ICF * Allogeneic SCT 90 to 180 days prior to enrollment * Able to comprehend and willing to provide informed consent * Willing and able to complete participant-assessment questionnaires either alone or with minimal assistance from a caregiver and/or trained site personnel
Exclusion criteria
* There are no
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Burden of cGVHD diagnosis and severity | 36 months |
Secondary
| Measure | Time frame |
|---|---|
| To describe personal and healthcare resources associated with the management of cGVHD | 36 months |
| To describe changes in the proteomic, cytologic and molecular profile in blood, serum and saliva cGVHD | Up to 36 months |
Countries
United States
Contacts
CONTACTIncyte Corporation Call Center (US)
CONTACTIncyte Corporation Call Center (ex-US)
Outcome results
None listed