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Analyses of Malnutrition Screening in Internal Medicine

Descriptive and Comparative Analyses of Malnutrition Screening in Internal Medicine

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05918900
Acronym
AMASIN
Enrollment
323
Registered
2023-06-26
Start date
2023-06-05
Completion date
2023-09-22
Last updated
2023-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malnutrition

Keywords

Malnutrition risk, Screening, Internal medicine, Nutritional Risk Screening 2002, Gastroenterology, Nephrology, Endocrinology, Rheumatology

Brief summary

The goal of this observational study is to study the presence and consequences of malnutrition risk in hospitalized internal medicine patients. The main questions it aims to answer are: 1. How many patients are at risk of malnutrition at admission? 2. Is there a link between an existing malnutrition risk and nutrition therapy that the patients receive? 3. Is there a link between an existing malnutrition risk and clinical outcome (e.g. length of hospital stay, mortality, need for rehospitalization)? Participants will be screened for malnutrition risk at admission using a validated questionnaire (Nutritional Risk Screening 2002). All relevant data regarding hospital stay will be obtained from the clinical information system after discharge.

Detailed description

Malnutrition is associated with adverse clinical outcome in hospitalized patients. Therefore, systematic screening for malnutrition risk at admission is recommended by almost all medical expert societies to identify patients who will benefit from nutritional therapy. Although clinical and economic benefit of systematic malnutrition screening have been shown in various settings and for different patient groups, such screening is still not mandatory in most countries. In part, establishment of malnutrition screening is hampered by discrepant findings on the prevalence of malnutrition risk and the lack of evidence on a local level. Hence, in this observational study the investigators examine the results of systematic malnutrition screening in internal medicine patients admitted to a university hospital in Northeast Germany. In particular, the investigators aim to determine the prevalence of malnutrition risk at hospital admission, the association between malnutrition risk and nutrition therapy as well as clinical outcome in different disciplines of internal medicine. For this purpose, all patients undergo screening for malnutrition risk at admission using a validated instrument (Nutritional Risk Screening 2002). All relevant data regarding the patients' hospital stay will be obtained from the clinical information system after discharge.

Interventions

None listed

Sponsors

University Medicine Greifswald
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* hospital admission for gastrointestinal, endocrine, rheumatic, or nephrological condition * provision of informed consent

Exclusion criteria

* inability to provide consent * unfeasibility to perform malnutrition screening within 48h after admission

Design outcomes

Primary

MeasureTime frameDescription
Overall presence of malnutrition riskBaselinePrevalence of malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, in all internal medicine patients at hospital admission. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.

Secondary

MeasureTime frameDescription
Presence of malnutrition risk in gastroenterologyBaselinePrevalence of malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, in patients with gastrointestinal disease at hospital admission. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Presence of malnutrition risk in endocrinologyBaselinePrevalence of malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, in patients with endocrine disease at hospital admission. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Presence of malnutrition risk in nephrologyBaselinePrevalence of malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, in patients with nephrological disease at hospital admission. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk to nutritional consultationBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and number of nutritional consultations. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk to nutritional diagnosisBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and nutritional diagnosis resulting from nutritional assessment by an expert dietitian. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Presence of malnutrition risk in rheumatologyBaselinePrevalence of malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, in patients with rheumatic disease at hospital admission. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk to intermediate care treatmentBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and admission to an intermediate care unit. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk to mortalityBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and in-hospital mortality. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk to length of hospital stayBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and length of hospital stay measured in days. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk and 30-day readmissionBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and unplanned hospital readmission within 30 days after discharge. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk and 90-day readmissionBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and unplanned hospital readmission within 90 days after discharge. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.
Relation of malnutrition risk to intensive care treatmentBaselineAssociation between malnutrition risk, i.e. Nutritional Risk Screening 2002 (NRS-2002) score \>= 3 points, and admission to an intensive care unit. NRS-2002 score ranges from 0 to 7, with higher values indicating greater nutritional risk.

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026