Dehydration
Conditions
Brief summary
The investigators want to understand the impact of the body losing and gaining water on brain function. Participants will restrict fluids consumed and exercise to lose 5% of body mass. Participants will then be provided fluid equal to the volume lost to consume over 2 hours (recovery). A series of brain function tests will be performed at baseline, following weight loss, and following recovery.
Detailed description
A baseline series of brain function tests will be performed. Following this, participants will complete a 24 hour fluid and water rich food restriction on the day proceeding testing. Participants will then complete moderate to high intensity exercise in a hot/humid room to achieve 5% body mass loss. Once baseline core body temperature returns to baseline levels, the series of brain function tests will be performed. Participants will then consume a sports drink equal to the volume of sweat lost over the course of a 2 hour recover period. Following this, he series of brain function tests will be performed.
Interventions
BEHAVIORALFluid loss and consumption
Upon 5% body mass loss, rehydration of fluid lost to sweating throughout a 2 hour recovery period
Sponsors
State University of New York at Buffalo
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 26 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy * Recreationally active * 18-26 years old
Exclusion criteria
* History of cardiovascular, metabolic, respiratory, neural, or renal disease * Hypertensive (systolic blood pressure ≥ 140 mmHg, diastolic blood pressure ≥ 90 mmHg) or tachycardic (resting heart rate ≥ 100 bpm) during the screening visit * Taking medication or supplements with a known side effect of affecting physiological responses to exercise (e.g., aspirin, acetaminophen, beta blockers, statins, stimulants, depressants, SSRIs) * Tobacco or nicotine use in the past six months * Current or past musculoskeletal injury impacting physical activity * Study physician discretion based on any other medical condition or medication
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Multitasking test | Upon completion of 5% body mass loss protocol, approximately 2 hours into the trial | Accuracy score of a multitasking test (0-100%) with greater scores indicating a better outcome |
Countries
United States
Outcome results
None listed