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AI-assisted White Light Endoscopy to Identify the Kimura-Takemoto Classification of Atrophic Gastritis

Artificial Intelligence-assisted White Light Endoscopy to Identify the Kimura-Takemoto Classification of Atrophic Gastritis to Achieve Gastric Cancer Risk Assessment

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05916014
Enrollment
1500
Registered
2023-06-23
Start date
2023-06-01
Completion date
2024-12-31
Last updated
2024-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence, Atrophic Gastritis, Endoscopy

Brief summary

Grading endoscopic atrophy according to the Kimura-Takemoto classification can assess the risk of gastric neoplasia development. However, the false negative rate of chronic atrophic gastritis is high due to the varying diagnostic standardization and diagnostic experience and levels of endoscopists. Therefore, this study aims to develop an AI model to identify the Kimura-Takemoto classification.

Detailed description

Grading endoscopic atrophy according to the Kimura-Takemoto classification can assess the risk of gastric neoplasia development. The higher the score, the more severe the degree of atrophic gastritis. However, the false negative rate of chronic atrophic gastritis is high due to the varying diagnostic standardization and diagnostic experience and levels of endoscopists. Therefore, this study aims to develop an AI model to identify the Kimura-Takemoto classification of atrophic gastritis to achieve gastric cancer risk assessment.

Interventions

DIAGNOSTIC_TESTDiagnostic Test: The diagnosis of Artificial Intelligence and endosopists

Endosopists and AI will assess the Kimura-Takemoto classification independently when the patients is eligible.

Sponsors

Linyi County People's Hospital,Dezhou,China
CollaboratorUNKNOWN
Shandong University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

Patients aged 18-80 years who undergo the white light endoscope examination Informed consent form provided by the patient.

Exclusion criteria

1. patients with severe cardiac, cerebral, pulmonary or renal dysfunction or psychiatric; 2. disorders who cannot participate in gastroscopy; 3. Patients with progressive gastric cancer; 4. low quality pictures; 5. patients with previous surgical procedures on the stomach or esophageal; 6. patients who refuse to sign the informed consent form;

Design outcomes

Primary

MeasureTime frameDescription
Accuracy of AI model to diagnose the Kimura-Takemoto classification2 yearsAccuracy of AI model to diagnose the Kimura-Takemoto classification
Sensitivity of AI model to diagnose the Kimura-Takemoto classification2 yearsSensitivity of AI model to diagnose the Kimura-Takemoto classification
Specificity of AI model to diagnose the Kimura-Takemoto classification2 yearsSpecificity of AI model to diagnose the Kimura-Takemoto classification

Secondary

MeasureTime frameDescription
The MIOU value of AI model in semantic segmentation of endoscopic atrophy picture2 yearsThe MIOU value of AI model in semantic segmentation of endoscopic atrophy picture

Countries

China

Contacts

Primary Contactyanqing Li, MD, PHD
liyanqing@sdu.edu.cn0531182169385

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026