Chronic Granulomatous Disease
Conditions
Brief summary
The primary study objective is to collect biospecimen samples (e.g., blood) from participants diagnosed with Chronic Granulomatous Disease (CGD). The biospecimens will be used to create a biorepository that can be used to identify disease associated biomarkers and potential targets with immune and multi-omics profiling. The disease sample collection and analysis will be the foundation for an extensive network of biospecimen access and linked datasets for future translational research.
Interventions
DIAGNOSTIC_TESTSpecimen Donation
blood donation
Sponsors
Sanguine Biosciences
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* The participant is willing and able to provide written informed consent * The participant is willing and able to provide appropriate photo identification * Participants aged 18 to 85 * Participants have been diagnosed with Chronic Granulomatous Disease (CGD) * Subjects who have a confirmed p47phox CGD mutation or Subjects who have a confirmed X-linked CGD mutation
Exclusion criteria
* Participants who are pregnant or are nursing * Participants with a known history of HIV, hepatitis, or other infectious diseases * Participants who have taken an investigational product in the last 30 days * Participants who have experienced excess blood loss, including blood donation, defined as 250 mL in the last month or 500 mL in the previous two months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Participants have been diagnosed with Chronic Granulomatous Disease (CGD) | 1 Year | Participants have been diagnosed with Chronic Granulomatous Disease (CGD) |
Countries
United States
Outcome results
None listed