Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05915637

Enrollment

336

Registered

2023-06-23

Start date

2021-09-01

Completion date

2022-11-01

Last updated

2023-06-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Brief summary

To investigate and analyze the status of preoperative frailty and its influencing factors in elderly patients with colorectal cancer using FRALL scale and other related scales, and to explore the correlation between preoperative frailty and early prognosis in elderly patients with colorectal cancer, so as to attract the attention of medical staff to preoperative frailty in this population and provide a preliminary research basis for the study of frailty intervention in these patients.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

60 Years to No maximum

Healthy volunteers

Inclusion criteria

1. age ≥60 years old; 2. Colorectal cancer was diagnosed according to the Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer (2020 edition) and planned to undergo elective laparoscopic radical resection of colorectal cancer; 3. able to complete physical assessment without communication barriers; 4. voluntarily participated in this study after informed consent.

Exclusion criteria

1. taking antidepressants, levodopa, donepezil hydrochloride and other drugs; 2. patients with preoperative colorectal cancer surgery or neoadjuvant therapy; 3. patients with TNM stage Ⅳ; 4. complicated with other malignant tumors except primary skin cancer or melanoma.

Design outcomes

Primary

Measure	Time frame	Description
Fatigue Assessment	7 days	Status of frailty will be assessed by FRALL Scale

Countries

China

Outcome results