Carpal Tunnel Syndrome, Pain, Chronic
Conditions
Brief summary
To assess the effectiveness of a combined physical and psychological intervention in reducing pain and improving function in carpal tunnel syndrome patients with nociplastic pain.
Interventions
OTHERCombined physical and psychological intervention
Physical therapy components will include splinting, tendon and nerve gliding exercises. Psychological components will include cognitive-behavioral therapy (CBT), delivered in individual sessions, targeting pain catastrophizing and fear of movement. Participants will attend 2 physical therapy sessions and one CBT session per week. for a period of 12 weeks
OTHERStandard care
Participants will be asked to wear a prefabricated wrist splint during the night and during strenuous activity. Also, they will receive tendon and nerve gliding exercises
Sponsors
Ahram Canadian University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
25 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Adults aged 25-65 years * Both sexes * Diagnosis of carpal tunnel syndrome based on clinical examination and nerve conduction studies * Presence of nociplastic pain as determined by the Central Sensitization Inventory (CSI) with a score ≥40 * Positive tinel and phalen sign.
Exclusion criteria
* Previous carpal tunnel release surgery * Other musculoskeletal or neurological disorders affecting the upper extremity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity using the Numeric Pain Rating Scale (NPRS) | Changes in pain intensity at baseline, 6 weeks, 12 weeks. |
| Functional ability using the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire | Changes in Functional ability at baseline, 6 weeks, 12 weeks. |
| Median nerve motor distal latency | Changes in Median nerve motor distal latency at baseline, 6 weeks, 12 weeks. |
| Median nerve sensory distal latency | Changes in Median nerve sensory distal latency at baseline, 6 weeks, 12 weeks. |
Secondary
| Measure | Time frame |
|---|---|
| Fear of movement using the Tampa Scale for Kinesiophobia (TSK) | Changes in Tampa Scale for Kinesiophobia (TSK) at baseline, 6 weeks, 12 weeks. |
| Grip strength measured using a hand dynamometer | Changes in Grip strength at baseline, 6 weeks, 12 weeks. |
| Pain catastrophizing using the Pain Catastrophizing Scale (PCS) | Changes in Pain Catastrophizing Scale (PCS) at baseline, 6 weeks, 12 weeks. |
Countries
Egypt
Contacts
Primary ContactMohamed M ElMeligie, Ph.d
Backup ContactAmal Fawzy, Ph.d
Outcome results
None listed