Pancreatic Neoplasms
Conditions
Keywords
Mutation, Genomics, Targeted Therapy, Cancer, Pancreas
Brief summary
This is a non-therapeutic exploratory observational precision oncology study designed to collect and analyze data that demonstrate the clinical efficacy and tolerability of personalized treatments based on molecular tumor profiling assessments (i.e., matched therapy) in adult pancreatic cancer patients. Patient medical records, obtained both retrospectively and prospectively, will be examined for results of molecular profiling obtained through standard of care testing to help understand how well molecular testing might predicts response to therapy. Patient demographic and outcome parameters to be evaluated include, but are not limited to, tumor response, time to treatment failure, patient survival, and toxicity.
Interventions
OTHERTargeted Therapy
Approved interventions based on the subject's genomic profile will be provided to investigators for consideration for anti-tumor therapy.
Sponsors
Medical College of Wisconsin
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years. * Pathologically confirmed pancreatic cancer. * Ability to understand a written informed consent document and the willingness to sign it
Exclusion criteria
* Age \<18 years. * Primary cancer diagnosis other than pancreatic cancer.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of Subjects Receiving Targeted Therapy | 5 years | This measure is the number of study subject's whose treating physician prescribes and subsequently receives the therapeutic recommendation of the Molecular Tumor Board. |
Countries
United States
Contacts
CONTACTCancer Center Clinical Trials Office
PRINCIPAL_INVESTIGATORMandana Kamgar, MD
Medical College of Wisconsin
Outcome results
None listed