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Perioperative Vaping Complications

Vaping Associated Perioperative Pulmonary Complications - Anesthetic Implications

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05912023
Enrollment
300
Registered
2023-06-22
Start date
2023-07-28
Completion date
2025-07-01
Last updated
2024-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication of Anesthesia, Vaping

Keywords

Vaping, Hypoxemia, Bronchospasm, Perioperative, Pneumonitis

Brief summary

Prospective observational study evaluating the incidence, and qualifying the types, of perioperative pulmonary complications in patients that vape.

Detailed description

The primary objective of our study is to determine the rate at which patients that vape or use e-cigarettes experience perioperative pulmonary complications during and following general anesthesia. Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated. A secondary objective will be to further investigate and include the relationship between vaping cessation timeline in the preoperative period and the occurrence of PPCs, which is similarly underreported in the literature. Furthermore, the study will assess how effectively anesthesia providers are screening for vaping or e-cigarette use as part of the preoperative evaluation, given that it is unclear whether anesthesiologists and surgeons routinely ask patients explicitly about vaping in the pre-operative setting. This lack of representative screening for vaping further obscures an understanding of the relationship between vaping, vaping cessation, and PPCs.

Interventions

None listed

Sponsors

Navy Medical Center San Diego
Lead SponsorFED

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to 80 Years

Inclusion criteria

* Surgical Patient * General Anesthesia * Hx of vaping * Age ≥12

Exclusion criteria

* Age \<12 * Pregnancy * Active preoperative pulmonary infection * Recent pulmonary infection (within 8 weeks) * Active tobacco smoker * Poorly controlled reactive airway disease (requires more than PRN albuterol) * Non-Lung Protective Ventilation

Design outcomes

Primary

MeasureTime frameDescription
Perioperative pulmonary complicationsFrom the initiation of general anesthesia through postoperative day seven.Complications of interest will include postoperative atelectasis with hypoxemia necessitating oxygen therapy, pneumothorax, pneumonia, bronchospasm, bronchospasm requiring bronchodilator therapy, exacerbation of underlying pulmonary disease, pneumonia, ARDS, and acute respiratory failure. Hospital course, including prolonged PACU stay, prolonged hospital admission for inpatients, and rate of ICU admissions, will also be investigated.

Secondary

MeasureTime frameDescription
Vaping cessation timelineFrom the initiation of general anesthesia through postoperative day seven.Includes the relationship between vaping cessation timeline in the preoperative period and the occurrence of postoperative pulmonary complications

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026