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Effects of Breaking Sitting on Human Behaviour and Metabolic Health

Effects of Breaking Prolonged Sitting on 24-h Human Behaviours, Self-feelings, Metabolic Health and Cognition in Healthy Adults

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05911490
Enrollment
24
Registered
2023-06-22
Start date
2019-12-20
Completion date
2020-09-29
Last updated
2023-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognition, Energy Balance, Metabolic Health, Physical Activity Level

Keywords

Breaking up sitting, Eating behaviour, Spontaneous physical activity, Executive function, Energy balance

Brief summary

This study primarily aimed to investigate effects of breaking up prolonged sitting with intermittent brisk walking in healthy young individuals on (1) post-trial human behaviours including energy intake and physical activity under free-living conditions and (2) cognitive performance in a simulated workplace environment.

Interventions

In the laboratory, after consuming 1st meal, participants sat on a chair for 180 min. After 180 min, the 2nd meal was provided. After finishing the 2nd meal, participants sat on a chair for another 120 min. After data collection was completed in the laboratory, participants were asked to keep wearing the same pedometer and to record any food and liquid consumption for the rest of the day (until midnight) under free-living conditions.

BEHAVIORALBreaking prolonged sitting

In the laboratory, after consuming 1st meal, participants walked 2 min on a treadmill every 20 minutes for the following 180 min. For the remainder of the time participants sat on the chair. After 180 min, the 2nd meal was provided. After finishing the 2nd meal, participants continued 2 min of walking every 20 min for the following 120 min. After data collection was completed in the laboratory, participants were asked to keep wearing the same pedometer and to record any food and liquid consumption for the rest of the day (until midnight) under free-living conditions.

Sponsors

Division of Endocrinology and Metabolism, Tri-Service General Hospital
CollaboratorUNKNOWN
National Taiwan Normal University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Without current and any history of brain injury, neurological disorder, cardiometabolic related diseases, diabetes or cancers. * Weight stable (not self-reported weight change ± 3 kg at least 3 months) * Body mass index (BMI) ranging between 18.5 to 27 kg/m2 * Can walk safely on a treadmill

Exclusion criteria

* Smokers, post-menopausal female, and volunteers who used any medications that could influence metabolic and inflammatory responses.

Design outcomes

Primary

MeasureTime frameDescription
Cognitive function320 minutesChanges in cognitive performance (% changes in reaction time) Task Switching and Flanker tasks
Physical activity level480 minutesChanges in physical activity level (steps) in the free-living conditions
Energy intake480 minutesChanges in energy intake (kcal) in the free-living conditions
Cognitive performance320 minutesChanges in cognitive performance (% changes in accuracy) including Task Switching and Flanker tasks

Secondary

MeasureTime frameDescription
Blood pressure320 minutesChanges in systolic blood pressure and diastolic blood pressure
Postprandial glucose concentrations320 minutesChanges in postprandial finger pricking glucose concentrations
Visual analogue scale (VAS)320 minutesChanges in self-perceived sensations including appetite, energy and mood (score from 0-100)
Continuous glucose monitoring320 minutesChanges in different depots of adipose tissue interstitial glucose concentrations

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026