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Optimizing Treatments for Heart Failure During Hospitalization

Optimizing Treatments for Heart Failure During Hospitalization

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05910437
Acronym
OPTICARD
Enrollment
184
Registered
2023-06-18
Start date
2023-08-08
Completion date
2023-11-29
Last updated
2026-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decompensated Heart Failure

Keywords

Decompensated heart failure

Brief summary

Heart failure reaches 1.5 million people in France and is responsible for 200,000 hospitalizations per year. Over the past ten years, new therapies have emerged (treatment of martial deficiency, Entresto, iSGLT2). Hospitalization in a context of acute heart failure is a moment of choice in the history of the disease to introduce recommended treatments under closer supervision (clinical, biological) than in ambulatory, and allows a decrease in hospitalizations, morbidity and mortality. The purpose of this study is to describe the introduction of heart failure drugs (including iSGLT2) in real-life settings in patients hospitalized for decompensated heart failure.

Interventions

OTHERHospitalized patient for decompensated heart failure

Describe the evolution of heart failure medications during hospitalization for decompensated heart failure.

Sponsors

Central Hospital, Nancy, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patient ≥ 18 years * Hospitalized (≥24h) for decompensated heart failure in cardiology.

Exclusion criteria

* Patient opposition participation in research and use of data.

Design outcomes

Primary

MeasureTime frameDescription
Prescription scoreDuring hospitalisation for decompensated heart failure (up to 10 days)Prescription score, ranging from 0 to 10, each type of heart failure treatment (IEC/ARA2, Sacubitril, betablockers, SGLT2i, MRA) being evaluated on a scale of 2.

Secondary

MeasureTime frameDescription
serum concentration of creatinineDuring hospitalisation for decompensated heart failure (up to10 days)Creatinine measured at admission and discharge
serum concentration of potassiumDuring hospitalisation for decompensated heart failure (up to 10 days)Potassium measured at admission and discharge
Concentration of hemoglobinDuring hospitalisation for decompensated heart failure (up to 10 days)hemoglobin measured at admission and discharge
All cause Death6 months
Rate of hospitalization for heart failure6 months

Countries

France

Contacts

STUDY_CHAIRNicolas GIRERD, MD-PhD

CHRU de NANCY

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 14, 2026