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Gathering Evidence on Best Practices for Lay Rescuer CPR Training

Generating Evidence to Optimize Lay Rescuer Cardiopulmonary Resuscitation (CPR) Training: a Longitudinal Study of Frequency, Modality, and Design Features Impacting Skill Retention

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05908500
Enrollment
2100
Registered
2023-06-18
Start date
2026-04-01
Completion date
2031-03-31
Last updated
2025-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Arrest, Out-Of-Hospital

Keywords

Cardiopulmonary Resuscitation, cardiopulmonary resuscitation training, Lay Rescuer cardiopulmonary resuscitation, lay rescuer cardiopulmonary resuscitation training

Brief summary

The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question\[s\] it aims to answer are: * What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR skill retention? * What is the impact of CPR manikin type (high-fidelity, inflatable, nontraditional objects) on skill retention? * How do specific features of training modality -- such as contextualization, gamification, and emotional engagement -- impact skill proficiency, knowledge retention, and attitudes about CPR? Participants will * Answer pre-training questionnaires * Participate in CPR training * Participate in CPR skills testing * Answer post-training questionnaires Researchers will compare different methods of training, different frequencies of training, and different manikin types.

Detailed description

Out-of-hospital cardiac arrest (OHCA) remains a major public health crisis in the United States, with over 350,000 cases annually and low survival rates. Lay rescuer cardiopulmonary resuscitation (CPR) can double survival, yet widespread gaps in training access, skill retention, and emotional readiness persist. While most U.S. states mandate high school CPR training, implementation quality varies, and traditional formats have remained unchanged for over 60 years. These methods are often time-consuming, expensive, and poorly suited for adolescents, leading to low participation and rapid skill decay. This study addresses these critical gaps by comparing various CPR training methods and procedures. The project tests the effectiveness of different training frequencies, durations, and delivery modes-including traditional instructor-led sessions, brief refreshers, and a novel, emotionally immersive serious game. The serious game leverages gamification, competition, and scenario-based learning to build emotional muscle memory and prepare students for real-world emergencies. Participants are enrolled from two high schools-one rural, one suburban-and randomized by class or individual into training arms with varied schedules and compression practice tools. These tools range from high-fidelity manikins to low-fidelity devices and improvised household objects. Outcomes include CPR performance metrics (compression rate, depth, recoil, and hand placement), knowledge retention, emotional engagement (measured via validated psychometric scales), and confidence in responding to cardiac arrest. Training sessions are delivered during the academic year, and students are assessed immediately after training and again at annual follow-up points. Data are collected in a de-identified format using school-issued ID numbers, ensuring participant confidentiality. Analysis will use generalized estimating equations and mixed-effects models to assess the impact of training method and frequency on skill retention and psychosocial readiness. The study also explores the role of contextualization, emotional engagement, and gamification as mediators of improved CPR performance. Ultimately, this multi-year trial aims to identify scalable, cost-effective strategies that optimize CPR training outcomes for lay rescuers. By improving technical skill retention and emotional preparedness, the study addresses key priorities for public health impact and aligns with NHLBI's strategic goals to reduce mortality from sudden cardiac arrest.

Interventions

BEHAVIORALCPR Training

Various durations and frequencies of CPR training

DEVICECPR Manikin Type

Various types of CPR manikins are compared

Sponsors

University of Nevada, Reno
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)

Masking description

The statistical analysis will be masked as to which intervention subjects received, with simple A, B, etc. designation.

Intervention model description

Aim 1: A 4-year, cluster-randomized trial at a rural high school evaluates the impact of CPR training frequency and duration on skill retention, confidence, and emotional readiness. Students (N\ 1,200) are assigned by class year to different training schedules using standard, gamified, or brief refresher formats. CPR skills, knowledge, and psychosocial outcomes are assessed annually. Aim 2: A 2-year, individually randomized trial at a suburban high school compares four chest compression practice tools: high-fidelity manikin, low-fidelity manikin, a novel no-head manikin, and improvised objects. Ninth-grade students (N\ 432) are assessed post-training and at 1 year for CPR skill quality (rate, depth, recoil, hand placement) using objective measurement tools.

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* All students at participating schools

Exclusion criteria

* Previous CPR training (will be included in the CPR training but excluded from analysis) * Physical injury which prevents performing CPR * Student or parent opt-out

Design outcomes

Primary

MeasureTime frameDescription
CPR Skill Retention1-4 yearsHigh-quality CPR as measured by compression rate (per minute), depth (inches), and correct hand placement. High-quality CPR is defined as correct rate (100-120/min) AND \>70% of compressions at appropriate depth (2-2.4inches) with appropriate hand placement.

Secondary

MeasureTime frameDescription
CPR Attitudes1-4 yearsParticipant confidence and intention to perform CPR, measured using Likert-scale items and validated engagement questionnaires.
CPR Knowledge Retention1-4 yearsPercentage of correct answers on a standardized multiple-choice test assessing CPR knowledge and AED use.
Emotional Profile1-4 yearsEmotional responses captured by the Positive and Negative Affect Schedule (PANAS), measuring affective realism and readiness.
Learner Engagement1-4 yearsSubjective engagement and perceived relevance of CPR training, measured via Likert scales and the Narrative Engagement Scale.

Other

MeasureTime frameDescription
Training Feature Effects (Contextualization, Gamification, Emotional Impact)1-4 yearsExploratory outcome assessing how specific training design elements influence CPR skills, knowledge, and self-efficacy through mediation and regression analyses.

Countries

United States

Contacts

Primary ContactLorrel Toft, MD
ltoft@unr.edu4103028456

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026