Parkinson Disease
Conditions
Brief summary
Previous work has shown that a statistical property of gait characterised by long-range autocorrelation functions is altered in Parkinson disease (PD). On the other hand it has been suggested that the same property is linked to the ability in healthy humans to co-regulate the amplitude and cadence of strides towards maintaining a constant speed. Here the investigators want to better understand why it is altered in PD by measuring the transitions between gait instructed by a metronome, and gait without metronome. The experimental conditions will allow the comparisons between these transitions across PD and healthy groups of volunteers, and assess differences based on statistical and computational modelling. The link with potential freezing episodes will also be studied to assess whether the statistical determinants of gait control in this population can be used as a proxy or predictor of the occurence of freezing episodes.
Interventions
OTHERWalking test
Walk with and without a metronome
OTHERDisease assessement
Disease stage assessed by a doctor
Sponsors
Université Catholique de Louvain
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients and volunteers able to walk for 20mins and without other neurological disorders.
Exclusion criteria
* Patients or volunteers unable to walk for 20mins and with other neurological disorders.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Stride cadence | Measured during the entire experiment (an average of 4.5 years) | Time between two consecutive heel strikes. Units are seconds. |
| Stride amplitude | Measured during the entire experiment (an average of 4.5 years) | Distance between two consecutive heel strikes. Units are meters. |
Countries
Belgium
Contacts
Primary ContactAndré Mouraux, PhD
Backup ContactFrederic Crevecoeur
Outcome results
None listed