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The Quality of Life in Individuals With Parkinson's Disease

A Cross-sectional Study - The Quality of Life in Individuals With Parkinson's Disease: Is it Related to Functionality and Tremor Severity?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05906693
Enrollment
52
Registered
2023-06-18
Start date
2019-01-01
Completion date
2021-07-13
Last updated
2023-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functionality, Parkinson Disease, Tremor

Keywords

Quality of Life, Upper Limb Functionality, Tremor, Electromyography, Parkinson's Disease

Brief summary

This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. The differences between Parkinson's Disease Quality of Life Questionnaire, Nine-Hole Peg Test, grip and pinch strength values in the individuals with and without tremor in the study were investigated.

Detailed description

Evaluating the relationship between Quality of Life and tremor is needed to determine the best physiotherapy and rehabilitation approaches for individuals with Parkinson's Disease. This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. Fifty-two individuals with Parkinson's Disease participated in the study. Quality of Life, tremor amplitude, upper limb functionality, grip and pinch strength were evaluated. The relationship of quality of life with tremor severity and upper limb functionality was examined in individuals with Parkinson's Disease. The results of individuals with and without tremor were compared.

Interventions

OTHERQuality of life

Parkinson's Disease Quality of Life Questionnaire (PDQ-39)

OTHERUpper limb functionality

Nine-Hole Peg Test

OTHERGrip and pinch strength

Dynamometer

OTHERTremor amplitude

Electromyography

OTHERDepression and anxiety levels

Hospital Anxiety and Depression Scale

The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale

Sponsors

Pamukkale University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* Definite diagnosis of idiopathic Parkinson Disease * Age between 40 and 80 years * Being literate * Having a grade between 1-4 from the Modified Hoehn and Yahr Scale * Having a score lower than 11 in Hospital Anxiety and Depression Scale

Exclusion criteria

* Who were with any other neurologic or orthopedic or rheumatologic disease affecting the upper extremity * Using antidepressants * Having vision loss * Deep brain stimulation

Design outcomes

Primary

MeasureTime frameDescription
Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale1 yearThe Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale. Used for the evaluation of clinical manifestations of Parkinson's disease. The scale consists of 4 subscales: the first part is Non-Motor Aspects of Experiences of Daily Living (13), the second part is Motor Aspects of Experiences of Daily Living (13), the third part is Motor Examination (33), and the fourth part is Motor Complications (6). The total number of items in the scale is 65. The minimum score is 0. The maximum MDS-UPDRS score is higher, given the additional items and scores for each body area, with a maximum score of 272. Higher scores indicate greater impact of Parkinson Disease symptoms.
Hospital Anxiety and Depression Scale1 yearThe Hospital Anxiety and Depression Scale aims to measure symptoms of anxiety and depression and consists of 14 items, seven items for the anxiety subscale (Hospital Anxiety and Depression Scale Anxiety) and seven for the depression subscale (Hospital Anxiety and Depression Scale Depression). Each item is scored on a response-scale with four alternatives ranging between 0 and 3. After adjusting for six items that are reversed scored, all responses are summed to obtain the two subscales. Both depression and anxiety subheadings are scored between 0 and 21. Higher scores indicate greater levels of anxiety or depression. Cut-off scores are 8-10 for doubtful cases and ≥11 for definite cases.
Parkinson's Disease Quality of Life Questionnaire (PDQ-39)1 yearUsed to assess the quality of life of Parkinson's patients
Electromyography1 yearUsed to assess the tremor amplitude of Parkinson's patients
Nine-Hole Peg Test1 yearUsed to assess the upper limb functionality of Parkinson's patients
Dynamometer1 yearUsed to assess the grip and pinch strength of Parkinson's patients

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026