Osteoporosis
Conditions
Brief summary
Fracture risk factors have long been identified as key factors in osteoporosis and fragility fractures. The WHO recommended Fracture risk assessmenttool (FRAX) applies clinical risk factors to assess the absolute risk of osteoporotic fractures in each individual. Our preliminary study suggests that FRAX estimates may underestimate the risk of fractures in the Chinese population. In order to optimize the risk prediction model of osteoporotic fractures, a treatment threshold and its optimal cutting point were initially established based on the data of the health management Center of the Second Xiangya Hospital of Central South University.
Interventions
OTHERRegular follow-up
Follow-up of the population was conducted to track the incidence of fractures
Sponsors
Second Xiangya Hospital of Central South University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
40 Years to 100 Years
Inclusion criteria
* Dual-energy X-ray bone mineral density measurement was performed in the health management center of our hospital in the physical examination subjects over 40 years old. Have independent civil capacity and agree to participate, and sign informed consent
Exclusion criteria
* Under 40 years of age， Patients who had undergone hip replacement or lumbar surgery and could not perform dual-energy X-ray BMD testing; Patients who have been treated with effective anti-osteoporosis drugs or have a history of malignant tumors.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bone mineral density bone mineral density | From 2021 to 2031 | Bone mineral density (BMD) data measured by dual-energy X-ray absorptiometry were collected from patients over 40 years old |
| Occurrence of fracture | From 2021 to 2031 | Follow-up of the population was conducted to track the incidence of fractures |
| clinical risk factors of osteoporotic fracture | From 2021 to 2031 | The main clinical risk factors of osteoporotic fracture were collected |
Countries
China
Contacts
Primary Contactzhifeng sheng, doctorate
Backup Contactchun yue, doctorate
Outcome results
None listed