Laparoscopic Pancreaticoduodenectomy
Conditions
Keywords
laparoscopic pancreaticoduodenectomy, pancreatic transection level
Brief summary
The level of pancreatic neck transection during laparoscopic pancreaticoduodenectomy (LPD) is not conclusive. Theoretically, the level of pancreatic transection can significantly affect the occurrence of postoperative pancreatic fistula (POPF) by influencing both the blood supply to the anastomosis and the location of the main pancreatic duct in the pancreatic transverse section. The investigators conduct a retropective propensity score-matched comparison to compare the impact of extended pancreatic transection and conventional pancreatic transection on POPF and the performance of the pancreaticojejunostomy during LPD.
Interventions
PROCEDUREextended pancreatic transection during laparoscopic pancreaticoduodenectomy
the pancreatic transection was performed at the pancreatic neck beyond the left side of the mesenterico-portal axis during laparoscopic pancreaticoduodenectomy
Sponsors
Xinrui Zhu，MD
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
1. consecutive patients underwent elective laparoscopic pancreaticoduodenectomy within October 2019 to April 2023 2. the perioperative and follow-up study data information can be collected completely 3. The level of pancreatic neck dissection can be determined by postoperative abdominal CT 4. patients without the history of neoadjuvant chemotherapy or radiotherapy
Exclusion criteria
1. conversion to laparotomy due to various reasons during operation; 2. combined with resection and reconstruction of the portal vein or the superior mesenteric vein 3. combined with other organ resection 4. the perioperative and follow-up study data information can not be collected completely, or the level of pancreatic neck dissection can not be determined by postoperative abdominal CT 5. patients with the history of neoadjuvant chemotherapy or radiotherapy 6. the main pancreatic duct did not be found during the operation, the duct-to-mucosa pancreaticojejunostomy could not be performed
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the incidence of clinically relevant pancreatic fistula | 3 months postoperatively | the incidence of the clinically relevant pancreatic fistula according the International Study Group of Pancreatic Surgery's definition and grading |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| surgical performance of pancreaticojejunostomy | intraoperatively | the duration of pancreaticojejunostomy |
| postoperative morbidity | 3 months postoperatively | postoperative morbidity (Clavien-Dindo score ≥3) within 3 months postoperatively |
| postoperative mortality | 3 months postoperatively | mortality within 3 months postoperatively |
Contacts
Primary ContactYunqiang Cai
Backup ContactBing Peng
Outcome results
None listed