Insulin Resistance in Atopic Dermatitis Patients

The Relationship Between Insulin Resistance and Disease Severity and Duration in Atopic Dermatitis Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05904509

Enrollment

Registered

2023-06-15

Start date

2022-09-01

Completion date

2023-10-01

Last updated

2024-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic Dermatitis

Keywords

atopic dermatitis, insulin resistance

Brief summary

The aim of the study is to determine the relationship between insulin resistance and disease duration and severity of atopic dermatitis.

Detailed description

The aim of the study is to determine the relationship between insulin resistance and disease duration and severity of atopic dermatitis. EASI and SCORAD values and disease duration of atopic dermatitis patients are calculated during the examination. HOMA-IR blood test result is compared with the results.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

2 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Atopic dermatitis patients confirmed by a dermatologist

Exclusion criteria

* patients younger than 2 years * patients older than 80 years * Atopic dermatitis patients without HOMA-IR result

Design outcomes

Primary

Measure	Time frame	Description
HOMA-IR	12 months	Patients' blood test show the result of fasting insulin (microU/L) x fasting glucose (mmol/L)/22.5
SCORAD index	12 months	Severity scoring of atopic dermatitis is calculated for each patient in the study. 6 intensity items (erythema, edema/papulation, oozing/crusts, excoriations, lichenification, dryness); 2 subjective symptoms(itch, sleeplessness); body surface area are studied. Max score is 103.
EASI index	12 months	Eczema Area and Severity Index is calculated for each patient in the study. Body surface area, 4 intensity items(erythema, induration, excoriation, lichenification) are studied. Max score is 72.
Duration of the disease	12 months	The time from the first onset of symptoms of the disease to the present. The relationship between insulin resistance and disease duration is examined

Countries

Turkey (Türkiye)

Outcome results