Effects of Platelet-Rich Fibrin on Knee Stability and Knee Function
Conditions
Keywords
Anterior cruciate ligament, platelet-rich fibrin, return to play
Brief summary
The study was conducted to investigate the effects of platelet-rich fibrin on knee stability, knee muscle strength and knee function in patients with ACL reconstruction. Thirty patients with ACL reconstruction were included to the study and randomly divided into two groups. Patients were assessed preoperative and at the postoperative 1-year.
Detailed description
The study was conducted yo investigate the effects of platelet-rich fibrin (PRF) on the knee stability and function in patients with anterior cruciate ligament (ACL) reconstruction. Thirty patients with ACL reconstruction were included to the study and randomly divided into two groups (PRF group and control group). Hamstring tendon autograft was used in all patients for the reconstruction of the teared ACL. A standardized postoperative rehabilitation program was applied to all patients. Patients' knee stability, knee muscle strength and knee function were assessed preoperatively and one-year postoperatively. Knee stability was assessed using KT-2000 Knee Arthrometer. Quadriceps femoris and hamstring muscle strength measurements were conducted with an isokinetic dynamometer at 60˚/sec and 180˚/sec angular velocities. One Leg Hop (OLH) and Y-Balance tests, and International Knee Documentation Committee (IKDC) were used to evaluate the knee function.
Interventions
BIOLOGICALPlatelet-Rich Fibrin during Standard ACL reconstruction surgery
Plateleth-rich fibrin was obtained from patients own blood (40 cc) and applied to the tunnels which were drilled for ACL graft
OTHERStandard ACL reconstruction surgery
This was a control group where patients received Standard ACL reconstruction surgery
Sponsors
Ankara City Hospital Bilkent
Hacettepe University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Randomised controlled design
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Being isolated ACL reconstruction, * Being between the ages of 18-45 years, * Performing sports recreationally or professionally
Exclusion criteria
* Having previous knee surgery, * Having systematic disease, * Having multiple ligament injury on the knee or additional cartilage injuries
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in the Knee Laxity | Preoperatively ans one year postoperatively | Knee laxity was measured using Kneelax-3 Knee arthrometer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in the Knee Muscle Strenght | Preoperatively ans one year postoperatively | Qudriceps and hamstring muscle strength were measured using an isokinetic dynamometer |
| Changes in the Knee Function | Preoperatively and one year postoperatively | Knee function was assessed with one leg hop (OLH) test and Y-Balance tests |
Outcome results
None listed