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Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy

Correlation of Biochemical Indexes and Retinal Hemodynamic in Patients With Different Degrees of Diabetic Retinopathy

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05902650
Enrollment
200
Registered
2023-06-15
Start date
2021-01-01
Completion date
2023-12-31
Last updated
2023-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Retinopathy

Brief summary

All OCTA data and biochemical indexes of diabetic patients were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.

Detailed description

Diabetic patients at the Department of Ophthalmology of the Seventh Affiliated Hospital of Sun Yat-sen University were selected as research participants. All OCTA data and biochemical indexes were acquired. A prediction model of diabetic retinopathy was built, and the random forest method was used to identify sensitive indicators.

Interventions

DIAGNOSTIC_TESTimaging

imaging

Sponsors

Mingzhe Cao
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Clinical diagnosis of diabetes

Exclusion criteria

* various other types of retinal and choroidal disease; * history of any intraocular surgery or treatment (including intravitreal injection, retinal photocoagulation etc. * with severe refractive medium opacity that could affect fundus examination.

Design outcomes

Primary

MeasureTime frameDescription
fasting blood glucose (FBG)the time of the patient's first 1 day visitbiochemical indexes
glycosylated hemoglobin (HbAlc)the time of the patient's first 1 day visitbiochemical indexes
OCTA datathe time of the patient's first 1 day visitAn image of the 3mm×3mm and 6 mm×6 mm macular areas detected by OCTA were captured. Quantitative analysis of vascular density and perfusion density of superficial capillary plexus in the macular area were automatically calculated using built-in software on the device.

Countries

China

Contacts

Primary ContactMingzhe Cao, Dr.
zhengz@mail.sysu.edu.cn13060822790

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026