Neurodevelopmental Abnormality, Transient Hypothyroxinemia of Prematurity
Conditions
Brief summary
• Transient hypothyroxinemia of prematurity (THoP) is defined as free thyroxine (FT4) level is below the reference values despite normal TSH level in preterm infant. This study aims to evaluate the neurological development of infants with transient premature hypothyroxinemia (THoP).
Interventions
OTHER'Ages and Stages Questionnaries' (ASQ)
''ASQ' is a screening tool for assessing the development of infants and preschoolers in the areas of communication, fine motor, gross motor, problem-solving and personal-social development, and 'ASQ:SE' is a screening tool for social-emotional development
Sponsors
Kanuni Sultan Suleyman Training and Research Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
No minimum to 1 Months
Healthy volunteers
Yes
Inclusion criteria
* newborn infants who were born at 28-36 gestational weeks * Infants who were hospitalized in the neonatal intensive care unit * Infants with transient hypothyroxinemia of prematurity
Exclusion criteria
* Newborns with maternal thyroid disease, * Severe intracranial issues, * Chromosomal and congenital anomalies, * Infants older than 36 gestational weeks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Long-term Neurodevelopment | 5 years | 'Ages And Stages Questionnaires' (ASQ) 'Ages And Stages Questionnaires: Social-Emotional' (ASQ:SE) Developmental Screening Tests evaluates the areas of communication, fine motor, gross motor, problem-solving and personal-social development. ASQ score differs 0-60 and results are interpreted in three group according to the gained points as normal, risky, and follow-up required. |
Countries
Turkey (Türkiye)
Outcome results
None listed