MicroRNAs From Blood Samples as Biomarkers for Gastric Cancer Detection

MicroRNAs From Blood Samples as Biomarkers for Gastric Cancer Detection: a Diagnostic Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05901376

Enrollment

280

Registered

2023-06-13

Start date

2023-04-25

Completion date

2025-06-30

Last updated

2023-06-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer, MicroRNAs

Brief summary

The goal of this observational study is to compare specific microRNA levels from the plasma of gastric cancer patients and healthy volunteers to see if there is an upregulated expression in gastric cancer patients. The main question it aims to answer is: \- Can microRNAs be effectively used as diagnostic biomarkers for gastric cancer? Participants will be asked for their consent to obtain 5 cc of blood.

Interventions

DIAGNOSTIC_TESTMicroRNA

MiR-20a, MiR-21, MiR-106b, MiR-199a, MiR-223

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

for Gastric Cancer group: * Recently diagnosed gastric cancer * Never received any treatment for gastric cancer Inclusion Criteria for Control group: * Age 50 or above * Underwent elective upper gastrointestinal endoscopy and negative for gastric cancer * No prior history of gastric dysplasia or cancer

Exclusion criteria

* Patients who cannot give informed consent * Pregnancy * Lymphoma

Design outcomes

Primary

Measure	Time frame	Description
The different of MiR-20a level between gastric cancer and control group	Day 1	The different of MiR-20a level between gastric cancer and control group
The different of MiR-21 level between gastric cancer and control group	Day 1	The different of MiR-21 level between gastric cancer and control group
The different of MiR-106b level between gastric cancer and control group	Day 1	The different of MiR-106b level between gastric cancer and control group
The different of MiR-199a level between gastric cancer and control group	Day 1	The different of MiR-199a level between gastric cancer and control group
The different of MiR-223 level between gastric cancer and control group	Day 1	The different of MiR-223 level between gastric cancer and control group

Countries

Thailand

Contacts

Primary ContactRapat Pittayanon

rapat125@gmail.com+662564000

Backup ContactKanik Sritara

pingsritara@gmail.com+66825254000

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026