Postoperative Pain
Conditions
Brief summary
in this study the investigators will investigate and compare the analgesic efficacy of two techniques (continuous TPVB and continuous ESPB) in relieving thoracotomy pain
Detailed description
General Anesthesia will be induced with Fentanyl (1-2 μg/kg), Propofol (2-3 mg/kg), and Atracurium (0.5-0.8 mg/kg). Pressure controlled Volume guarantee Ventilation mode will be used to maintain O2 Saturation Above 98% and End tidal co2 Around 30-35 mmHg. Anesthesia will be maintained with Isoflurane 1.2 Minimum Alveolar Concentration inhalation after induction Group A: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous infusion U/S-Guided TPVB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative and Group B: Patients will receive Loading dose of 20 ml 0.25% bupivacaine then continuous U/S-Guided ESPB of 5 ml/h of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.
Interventions
continuous infusion U/S-Guided TPVB of 5 ml/hr of 0.125% bupivacaine started through the catheter before the surgical procedure intraoperative.
continuous U/S-Guided ESPB of 5 ml/hr of 0.125% bupivacaine started through the catheter before the surgical procedure
Sponsors
Mohamed Emad Basune
Wesam Eldin Sultan
Rabab Mohammed Habeeb
Amal Gouda Elsayed Safan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
\- Eligible 40 patients will be older than 21 years old with American society of anesthesia physical status I& II scheduled for elective thoracotomy
Exclusion criteria
* Patients who are: * Uncooperative. * Having allergy to any of the study drugs. * Known abuse of alcohol or medication. * Having Local infection at the site of injection or systemic infection. * Pregnancy. * With coagulation disorders or on anticoagulation therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Compare the VAS score postoperative of (U/S)-guided continuous (ESPB) to continuous (TPVB) following thoracotomy | 48 hours | visual analogue scale (VAS) Score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 1 st call analgesia | 1 hour | mg |
| Total rescue opioid dose used | 48 hour | mg |
| patient satisfaction at 24 hours | 24 hours | — |
| occurrence of adverse events | 24hours | — |
| hospital stay | 1 week | days |
Countries
Egypt
Outcome results
None listed