Rehabilitation, Stroke
Conditions
Keywords
rehabilitation, stroke, nature-based, therapy, microbiome, gut-brain axis
Brief summary
Stroke rehabilitation patients are subjected to additional nature-based therapies during a rehabilitation ward period.
Detailed description
Inward stroke rehabilitation patients are selected randomly into two groups: intervention and control groups in proportions 1-2:1. Blood samples and microbiome samples of saliva, skin and feces are taken from all patients prior to interventions. These are controlled after 4 weeks from the beginning of the study and 3 months after signing-off the ward. Questionnaires eg on moods, life quality and function deficits are conducted in the beginning of the study, after 4 weeks from the start and 3 months after signing-off. Physiological measurements will be done to observe autonomic nerve status. The interventions consisting of therapy sessions in the hospital nearby nature will be conducted thrice a week one of them being an individual nature-visit with the research worker, one in group and one with family-member or volunteer. The moods and quality of life of the family-member participating in the study will also be followed up. The control group is advised to do simple, more conventional rehabilitative tasks indoors.
Interventions
PROCEDURENature-based therapy
Therapy sessions conducted outdoors
Sponsors
Helsinki University Central Hospital
University of Jyvaskyla
Tampere University
University of Eastern Finland
Natural Resources Institute Finland
University of Helsinki
Joint Authority for Päijät-Häme Social and Health Care
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Randomised controlled study, intervention and control groups
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Acute/Subacute stroke * Rehabilitation ward patient
Exclusion criteria
* Incapable of independent decision making * Traumatic bleeding in brain tissue * Severe aphasia * Severe, malign ongoing disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional ability | 0-30 days | Evaluation of functional ability in intervention and control groups by Patient-Reported Outcomes Measurement Information (PROMIS) questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life by WHO Disability Assessment Schedule (WHODAS) | 0-30 days | Evaluation of quality of life in intervention and control groups, measured by WHODAS questionnaire. |
| Assessment of the intervention impacts on rehabilitation | 0-120 days | Evaluation of the impact of intervention into achieving the predetermined goals of rehabilitation. Measured by Goal Attainment Scale (GAS) in intervention and control group. |
| Psychological or psychotherapeutic effects | 0-30 days | Evaluation of the effect of interventions to psychological well-being or psychotherapeutic effect in comparison to control groups. Measurement by Core-10-survey. |
| Intervention effects on microbiome | 0-120 days | Measurement of the effect of intervention on participant microbiome compared to participant microbiome in the control group. Microbial analyses of stool, saliva and flakes of skin. |
| Intervention effect on the activity of autonomic nerve system | 0-30 days | The activity of autonomic nerve system is measured with a portable device recording eg heart rate and activity. The activity of autonomic nerve system is measured both in intervention and control group. |
Countries
Finland
Contacts
Primary ContactHanna Haveri, MD PhD
Backup ContactMarja Mikkelsson, Prof
Outcome results
None listed