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Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After Primary Anterior Cruciate Ligament Reconstruction

Association Between 4-Month Isokinetic Testing Measures and Second Knee Injuries After

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05897970
Acronym
PREDICT-ACLv2
Enrollment
150
Registered
2023-06-12
Start date
2021-05-01
Completion date
2023-05-01
Last updated
2025-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACL Injury, Knee Injuries, Muscle Weakness

Brief summary

Anterior cruciate ligament (ACL) is a frequent and disabling injury in athletes. Most of the time, ACL reconstruction (ACLR) is consider for regaining function and returning to preinjury sports while reducing the risk of secondary injuries. However, the risk of secondary severe knee injury is increased after ACLR, especially in athletes returning to strenuous activities. If strength symmetry is considered as an important factor in the Return-to-sport (RTS) decision, there is conflicting data about the association between strength symmetry and the risk of second knee injury after ACLR. The main objective of this study was to test if knee muscles strength symmetry at 4 months was associated with the psychological readiness and incidence of subsequent severe injury of both knees at a minimum 2 years follow-up after ACL-R.

Interventions

DIAGNOSTIC_TESTReturn-to-sport (RTS) follow-up

All sports patients who had a muscle evaluation at 3-4 months after ACLR since January 2017

Sponsors

University Hospital, Caen
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
16 Years to 55 Years

Inclusion criteria

Patients who have had an ACL reconstruction surgery (isolated or associated with other meniscal or ligamentary surgery) Patient included in the sport medicine follow-up protocole with intermediate and final isokinetic muscular assessment at 3-4 months Patient who received the information form Patients with access to the Internet

Exclusion criteria

Patient who did not participate in all follow-up consultations and isokinetic muscular assessments Patients who had a previous knee surgery before the ACLR Cognitive or sensory impairment making it impossible to understand the information form Neurological, traumatic or osteoarticular history responsible for muscle imbalance prior to surgery

Design outcomes

Primary

MeasureTime frameDescription
Change in StrengthACL group: Two evaluations on both injured and healthy knees: 3-4 months after surgery; Routine practice following guidelines]Measurement of knee extensors and flexors peak strength (in newton.meter, Nm) on isokinetic dynamometer.

Secondary

MeasureTime frameDescription
Individual characteristicsACLR group: Two follow-up medical consultations: (1) 4 months after surgery and (2) 2 years after the surgery for return to sport and reinjury;Personal characteristics recorded in the medical report as age, gender, type of sport and sport level of practice and return to sport after the surgery and severe reinjury on the operated knee or contralateral knee.
Surgery characteristicsACLR group: Two follow-up medical consultations 4 months after surgerySurgery characteristics recorded in the medical report as the type of surgery, the surgery duration
Re-injuriesACLR group: One evaluation with a minimum 2 years follow-up after the surgeryWeb based questionnaire about any sever knee injury (meniscus or ACL) after the primary ACLR
Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) scale.ACLR group: One evaluation with a minimum 2 years follow-up after the surgeryWeb based questionnaire with completion of the Anterior Cruciate Ligament-Return to Sport after Injury (ACL-RSI) scale.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026