Skip to content

Foveal Sparing ILM Peeling With ILM Flap Transposition

Foveal Sparing ILM Peeling With ILM Flap Transposition

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05897671
Enrollment
42
Registered
2023-06-09
Start date
2023-06-01
Completion date
2023-06-01
Last updated
2023-06-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Full Thickness Macular Hole

Brief summary

Foveal sparing internal limiting membrane (ILM) peeling with ILM flap transposition over the macular hole combines the benefits of foveal sparing ILM peeling with ILM flap techniques. Aim of this study is to retrospectively examine the rate of postsurgical macular hole closure, development of central atrophy in the foveal area, and improvement of best corrected distant visual acuity in a group of patients having undergone foveal sparing ILM peeling with ILM flap transposition for macular hole repair.

Detailed description

Idiopathic full thickness macular holes lead to central defects in the visual field and to deterioration of the visual acuity. Introduction of internal limiting membrane (ILM) Peeling techniques lead to significant increase in closure rates of the macular holes. Foveal sparing ILM peeling represents a surgical technique for macular hole repair with less surgical trauma with high closure rates of the macular hole, compared to classic ILM Peeling \[Ho et al. 2014, Murphy et al 2019\]. The combination of foveal sparing ILM Peeling with the established ILM flap techniques \[Michalewska et al 2010 und 2015\] offers the potential of better improvement in postsurgical visual acuity with the high closure rates, due to ILM flaps. Aim of this study is to retrospectively examine the rate of postsurgical macular hole closure, development of central atrophy in the foveal area, and improvement of best corrected distant visual acuity in a group of patients having undergone foveal sparing ILM peeling with ILM flap transposition for macular hole repair.

Interventions

Macular hole closure rate, visual acuity and OCT

Sponsors

Vienna Institute for Research in Ocular Surgery
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Vitrectomy with foveal sparing ILM peeling with ILM flap transposition in the time period from 1.10.2020 to 8.7.2022 * Age 18 and older * Idiopathic full thickness macular hole as indication for surgery * Full follow-up, including visual acuity testing and OCT preoperative, and 3 months after surgery.

Exclusion criteria

* Age \<18 years

Design outcomes

Primary

MeasureTime frameDescription
macular hole closure rateup to 3 months after surgerypostsurgical closure of macular holes is examined from routine postsurgical optical coherence tomography (OCT) imaging

Secondary

MeasureTime frameDescription
visual acuity3 monthsvisual acuity before and 3 months after surgery is examined
OCT3 monthsmeasurements of macular hole diameters from presurgical OCTs and restoration of the ellipsoid zone (EZ) 3 months after surgery is analysed

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026