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THE EFFECT OF RADIOFREQUENCY ON POSTMENOPAUSAL ADIPOSE TISSUE

THE EFFECT OF RADIOFREQUENCY ON POSTMENOPAUSAL ADIPOSE TISSUE

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05895435
Enrollment
60
Registered
2023-06-08
Start date
2023-05-31
Completion date
2023-10-18
Last updated
2023-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Show Positive Effect of Radiofrequancy on Postmenopausal Adipose Tissue

Brief summary

* Menopause is associated with a redistribution of adipose tissue towards central adiposity, known to cause insulin resistance. It was found that menopause was associated with changes in adipose tissue phenotype related to metabolic dysfunction. In subcutaneous adipose tissue (SAT) * The radiofrequency uses high-frequency electromagnetic waves to produce heat at the cutaneous and the subcutaneous levels. The mechanism of action, through the vibration of water molecules, transforms the electromagnetic energy into thermal. The heat generated by conversion occurs under 30 kHz to 300 MHz, and the most frequently used frequency is set between 0.5 and 1.5 MHz. The RF mechanism of fat reduction occurs by the generation of thermal stimulation of adipocyte metabolism, occurring through enzymatic degradation by lipase-mediated triglycerides, apoptosis, and adipocyte rupture and the objective of study to show the positive effect of radiofrequancy on postmenopausal adipose tissue

Detailed description

About 90% of menopausal women experience some amount of weight gain. It is a natural and common aspect of getting older. It occurs because the body mass increases, as a result of fat deposits. However, weight gain associated with menopause typically involves increased amounts of fat around the abdomen. On an average, women gain between 8-10 kilogram between the ages of 45 and 55, the stage in life when menopause occurs. This extra weight generally does not evenly distribute itself throughout a woman's body. The weight tends instead to accumulate around the abdomen or thighs (Singh et al., 2013). Postmenopausal women are usually troubled by increasing weight and waist circumference caused by obesity and android fat redistribution it is mostly attributed to estrogen depletion though other factors such as chronological aging and decline in physical activity play a significant role. The deleterious health consequences of obesity and visceral fat deposition after menopause encompass a variety of problems; from dyslipidemia and metabolic syndrome to increased risk of cardiovascular disease (CVD), osteoporosis, malignancies and mortality (Stachowiak et al., 2015) This emphasizes the need of effective methods for treating central adiposity in post-menopausal woman. No prior studies have investigated the effect of radiofrequency on adipose tissue. So this may add a new physical therapy method for treating this problem.

Interventions

* Power of device: 150 W * Duration of the session: 40 minutes * Frequency: 2 sessions per week for 8 week. * Heating temperature: According to patient tolerance.

OTHERaerobic exercise

The program include five minutes for warming-up in the form of range of motion and stretching exercises, thirty minutes of walking on treadmill with high speed (60-70% of maximum heart rate) and five minutes of cooling down (on treadmill with low speed and without inclination

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
FEMALE
Age
45 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* 1-Their ages will be ranged from 45 to 60 years 2- BMI \> 25 kg/m² and \< 35 kg/m². 3- Waist circumference more than 88cm

Exclusion criteria

* 1-Cancer. 2-Renal failure 3-tumors 4-Hepatic diseases 5-skin disease that prevent the use of radiofrequancy

Design outcomes

Primary

MeasureTime frameDescription
total cholestrol and HDL and LDL and triglycerides and VLDL by blood analysis8 weekmeasure before and after tratement programm

Secondary

MeasureTime frameDescription
waist circumferance using tape measurment8 weekmeasure before and after tratement
body mass index8 weekmeasure before and after tratement
weight8 weekmeasure before and after tratement

Contacts

Primary Contactmahmoud adel darahem
mahmouddarahem2023@gamil.com01028911100
Backup Contactafaf mohamed botla
drafafmohamed@cu.edu.eg01283126608

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026