Analgesia
Conditions
Brief summary
The analgesic efficacy of different volumes in ESPB patients undergoing single-level lumbar spine fixation
Detailed description
The erector spinae plane block (ESPB) its an interfacial plane block for an effective treatment for thoracic neuropathic pain. Currently, compared to the use of opioids, the ESPB has fewer side effects and is safe for patients of all ages having abdominal and thoracic operations .
Interventions
Bilateral ultrasound guided in erector spinae plane block by bupivacaine 0.25%
Sponsors
Kafrelsheikh University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Aged 18-65 years. 2. Both genders. 3. American Society of Anesthesiologists' (ASA) physical status I or II. 4. Undergoing single level lumbar spine fixation.
Exclusion criteria
1. Patient refusal. 2. Pregnant females. 3. Renal, lung, heart, or liver disorders. 4. Communication difficulties which might prevent a reliable postoperative assessment. 5. Contraindication to regional anesthesia (bleeding disorder, use of any anticoagulants, local infection, known allergy to local anesthetics). 6. BMI more than 30 kg/m2.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total morphine consumption | First 24 hours postoperatively | Patients were allowed to receive incremental doses of morphine 3mg intravenously if numerical rating scale pain score will be ≥ then the total amount of morphine will be recorded |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Numerical rating scale | Up to 48 hours postoperatively | Postoperative pain using numerical rating scale (NRS) will be measured at post-anesthesia care unit, from 0 to 10, with 0 representing no pain and 10 representing maximum intolerable pain |
| Time to the first rescue analgesic | Up to 24 hours postoperatively | If numerical rating scale \>4 was observed, rescue analgesia (morphine 3 mg IV) was administered |
| Postoperative complications | Up to 24 hours postoperatively | postoperative nausea and vomiting (PONV), hypotension (mean arterial pressure \< 20% of baseline readings and was managed by ephedrine 5 mg IV and/or normal saline IVI), bradycardia (heart rate \< 60 beats/min and was managed by atropine 0.6 mg IV). |
| 5-point scale | Up to 24 hours postoperative | The degree of patient satisfaction was assessed on a 5-point scale: (0= extremely dissatisfied, 1= unsatisfied, 2= neither satisfied nor unsatisfied, 3= satisfied), and 4= extremely satisfied). |
Countries
Egypt
Outcome results
None listed