Type 1 Diabetes
Conditions
Brief summary
Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes have concluded that bone is negatively affected in type 1 diabetes with impaired bone density,increased fracture risk and impaired bone turnover markers.
Interventions
DIAGNOSTIC_TESTserum ostecalcin,serum sclerostin and parathroid profile
evaluation of bone turnover markers in blood
Sponsors
Sohag University
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
3 Years to 16 Years
Healthy volunteers
Yes
Inclusion criteria
* childern and adolsecents below 16 years of age diagnsed with type 1 diabetes for at least 1 year age and sex-matched control childern and adolsecents will be included
Exclusion criteria
* childern and adolescents with congenital bone disease, those with disorders of the parathyroid gland and those with chronic kidney disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| level of serum ostecalcin, sclerostin in patients with type 1 diabetes ann d their age and sex matched control | 12 months | markers of bone turnover in patients with type 1 diabetes and their matched control |
Countries
Egypt
Contacts
Primary ContactHajar M Ismail, resident
Backup ContactAhmed M Monir, assistant professor
Outcome results
None listed