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Electrophysiological Signatures of Distinct Working Memory Subprocesses That Predict Long-term Memory Success

Electrophysiological Signatures of Distinct Working Memory Subprocesses That Predict Long-term Memory Success

Status
Enrolling by invitation
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05892419
Acronym
WMLTM
Enrollment
96
Registered
2023-06-07
Start date
2022-07-01
Completion date
2026-07-31
Last updated
2023-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

EEG, Memory

Brief summary

Healthy young adults will view pictures of items while the investigators record electroencephalogram (EEG) brain activity. Then, the investigators will ask the participants to report which items the participants remember seeing. The investigators will examine how the measured brain activity relates to which pictures the participants remember.

Detailed description

Electrophysiological signatures track distinct subprocesses of working memory, including the number of items and the spatial locations of those items. By identifying how these subprocesses predict long-term memory success in healthy young adults, this project should lead to an intricate understanding of the relationship between working memory and long-term memory. This study will investigate when and how long-term memory failures arise, by using sophisticated machine learning analyses of neural data. Moreover, this study will test the extent to which the investigators can track working memory processes in real time and how the investigators can leverage that information to improve long-term memory success. This will inform basic theories of the relationship between working memory and long-term memory and motivate future applications.

Interventions

OTHERNo intervention

There is no intervention

Sponsors

University of Chicago
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
OTHER

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years

Inclusion criteria

* normal or corrected to normal vision

Exclusion criteria

* non-fluent in English

Design outcomes

Primary

MeasureTime frameDescription
Memory performanceThis task is performed multiple time within the experimental session, which in total lasts around 3 hours.To measure recognition memory performance, participants will view pictures and respond as to whether they remember previously seeing these items. Participants will be shown both old and new items. In the long-term memory phase, they will report their confidence at having seen each image using a four point rating scale, ranging from being confident the item is new (i.e., not previously seen) to being confident the item is old (i.e., previously seen).

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026