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Ridge Preservation Using Different Techniques

Soft Tissue Contour and Radiographic Evaluation of Ridge Preservation Using Different Techniques

Status
Enrolling by invitation
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05892016
Enrollment
130
Registered
2023-06-07
Start date
2023-02-28
Completion date
2026-03-31
Last updated
2023-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Ridge Augmentation, Connective Tissue, Membranes; Retained, Tooth Extraction

Keywords

Alveolar Ridge Preservation Connective tissue graft, Tooth extraction, Membranes

Brief summary

Soft tissue contour and radiographic evaluation of alveolar ridge preservation using different techniques Background: Following tooth extraction, the alveolar ridge undergoes an inevitable remodeling process which influences future implant therapy or prosthetic rehabilitation in the edentulous area. In an attempt to attenuate the loss of hard and soft tissue after tooth loss, alveolar ridge preservation (ARP) immediately after complete tooth extraction could minimize the need for ancillary ridge augmentation or soft tissue grafting. Different techniques and barrier membranes has been proposed to achieve the sealing of extraction socket. Aim: To investigate the effect of different techniques and barrier membranes for the soft tissue contour and morphological change of alveolar ridge after ARP Methods: The study was designed as a randomized controlled trial and recruited patients, who require ARP for the purpose of implant placement or prosthodontic rehabilitation. After the tooth extraction, patients were randomly allocated to one of the following groups: ridge preservation with a xenogeneic bone substitute and (a) spontaneous healing (control), (b) covered with a free palatal graft, (c) or covered with pedical palatal graft, (d) covered with a collagen membrane, (e) covered with a non-resorbable high-density polytetrafluoroethylene membrane. 2 weeks, 4 weeks, 12 weeks, and 24 weeks following tooth extraction and ARP, clinical profilometric and radiographic evaluations were performed to analyze the change of hard and soft tissue contour. Moreover, and the need for additional guided bone regeneration (GBR) or soft tissue augmentation were assessed prior implants or fixed prosthesis placement.

Interventions

PROCEDUREAlveolar ridge preservation

grafted with bone particle and covered with a subepithelial connective tissue graft

Sponsors

Tri-Service General Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)

Intervention model description

1. spontaneous healing (control) Alveolar ridge preservation grafted with bone particle and 2. covered with a free palatal graft 3. covered with pedical palatal graft 4. covered with a collagen membrane 5. covered with a non-resorbable high-density polytetrafluoroethylene membrane.

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* \>20 years old * No contraindications for invasive dental procedures. * Not pregnant. * Teeth need to be extracted due to malocclusion or broken teeth. * Requires dental implant or denture fabrication after tooth extraction. * Healthy soft tissue (probing bleeding index \<20%, plaque index \<20%). * At least 2mm of keratinized gingiva on the buccal and lingual sides. * No need for simultaneous bone augmentation surgery during implant placement. * Willing to participate in and sign the consent form for this trial.

Exclusion criteria

* Poor oral hygiene maintenance. * Uncontrolled periodontal disease. * Heavy smoker (smokes \>20 cigarettes per day). * Uncontrolled diabetes. * Alcohol abuse. * Currently receiving medication treatment affecting wound healing (osteoporosis medication, radiation or chemotherapy).

Design outcomes

Primary

MeasureTime frameDescription
Soft tissue alternationup to 12 monthscone-beam computed tomography data and STereoLithography files are superimposed to measure the soft tissue dimensions.
Hard tissue alternationup to 12 monthscone-beam computed tomography data and STereoLithography files are superimposed to measure the hard tissue dimensions.

Secondary

MeasureTime frameDescription
Keratinized tissue width changesup to 12 monthsUse periodontal probe to measurement.
Visual Analogue Scale14 daysAsk the patient to fill out the questionnaire

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026