Donor, Liver Transplantation, Postoperative Pain
Conditions
Brief summary
Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors. Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.
Detailed description
Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.
Interventions
External oblique intercostal plane block will be administered at the end of the surgery and after skin closure.
OTHERExternal oblique intercostal plane block
External oblique intercostal plane block will be administered at the end of the surgery and after skin closure. .
Sponsors
Istinye University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Age between 18 and 75 years * Patients with American Society of Anesthesiology (ASA) physical status I-II * Patients scheduled for a living donor hepatectomy
Exclusion criteria
* Allergy to local anesthetics * Coagulopathy * Skin infection at the block area * Advanced renal failure * Chronic pain syndromes * Alcohol or drug abuse * Psychiatric disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Morphine consumption | Postoperative 24 hours | The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Postoperative visual analog scale scores | Postoperative 24 hours | Postoperative pain will be assessed using a visual analog scale (VAS) (from 0 = no pain to 10 = maximum possible pain) for the first 24 hours. |
| Rescue analgesic drug consumption | postoperative 24 hours | The amount of rescue analgesic in mg required by the patient will be recorded for the first 24 hours. |
| Incidence of postoperative nausea and vomiting | postoperative 24 hours | Number of patients developing postoperative nausea and vomiting will be recorded for the first 24 hours |
Countries
Turkey (Türkiye)
Outcome results
None listed