Pulmonary Aspiration
Conditions
Brief summary
The purpose of this study is to determine the type of gastric content and quantify the volume of liquid gastric contents using ultrasonography in patients on GLP-1 agonists that have presented for elective surgery and to determine if risk factors are associated with a higher gastric volume in patients on GLP-1 receptor agonists.
Interventions
DIAGNOSTIC_TESTGastric ultrasound
Patient will be scanned first in the supine position and then in the right lateral decubitus position. The ultrasound probe will be placed in a sagittal plane in the epigastric region at the left subcostal margin and then will be moved past the midline in a fan like manner to the right subcostal region. Qualitative and quantitative assessments will be done.
Sponsors
The University of Texas Health Science Center, Houston
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients taking GLP-1receptor agonists (N=62) * Patients not taking GLP-1 receptor agonists (N=62)
Exclusion criteria
* Previous gastric resection or bypass * Gastric band in situ * Previous fundoplication * Large hiatal hernia * Pregnant patients * Recent trauma * Inability to turn to the right lateral decubitus position
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of subjects that are at risk for aspiration | end of ultrasound | Risk for aspiration is indicated by the presence of solids, thick fluid, or clear fluids \>1.5ml/kg in the gastric antrum in the right lateral decubitus position |
| Number of subjects that are at low risk for aspiration | end of ultrasound | Low risk for aspiration is indicated by a collapsed gastric antrum or clear fluids \<1.5ml/kg in the gastric antrum in the right lateral decubitus position. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants that are female as indicated in the medical records | end of ultrasound | — |
| Body mass Index (BMI) | end of ultrasound | Body Mass Index (BMI) is calculated as the body mass in kilograms (kg) divided by the square of the body height in meters, and is expressed in units of kg/m2. |
| Physical status as assessed by the American Society of Anesthesiologists (ASA) physical status classification system | end of ultrasound | The classification ranges from American Society of Anesthesiologists (ASA)1 (normal healthy person ) to ASA IV (A patient with severe systemic disease that is a constant threat to life) |
| Number of participants with diabetes | end of ultrasound | — |
| Age | end of ultrasound | — |
| Pain severity as assessed by the numeric scale | end of ultrasound | This is a 11 point scale with scores ranging from 0 (no pain) to 10 (worst imaginable pain) |
| Number of participants with Gastroesophageal reflux disease (GERD) | end of ultrasound | — |
| Number of participants that have use opioids preoperatively | end of ultrasound | — |
| Number of participants with reported nothing by mouth (NPO) status | end of ultrasound | — |
| Number of participants that are male as indicated in the medical records | end of ultrasound | — |
Countries
United States
Outcome results
None listed