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Predictors of Postoperative Atrial Fibrillation After CABG

A Comprehensive Observational Study on the Determinants of Postoperative Atrial Fibrillation in Patients Undergoing Coronary Artery Bypass Grafting

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05888168
Acronym
CODA-AF
Enrollment
15000
Registered
2023-06-05
Start date
2018-01-01
Completion date
2024-05-01
Last updated
2023-06-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation New Onset, Coronary Artery Disease

Keywords

coronary artery bypass grafting, postoperative atrial fibrillation

Brief summary

This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.

Detailed description

Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.

Interventions

PROCEDURECABG

All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.

Sponsors

Kun Hua
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Adults aged 18 years or older. * Patients who underwent CABG.

Exclusion criteria

* Patients with a history of preoperative atrial fibrillation or other significant arrhythmias. * Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG. * Patients who cannot provide informed consent or lack adequate follow-up information.

Design outcomes

Primary

MeasureTime frameDescription
Incidence of POAFDuring hospital stay, up to 30 daysThis will be determined based on electrocardiograms (ECG) and/or relevant medical records, within 30 days post-CABG.

Secondary

MeasureTime frame
Hospital length of stayDuring hospital stay, up to 30 days
ICU admission timeDuring hospital stay, up to 30 days
Number of participants with StrokeDuring hospital stay, up to 30 days
MortalityDuring hospital stay, up to 30 days

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 8, 2026