Atrial Fibrillation New Onset, Coronary Artery Disease
Conditions
Keywords
coronary artery bypass grafting, postoperative atrial fibrillation
Brief summary
This observational study aims to identify the determinants or predictors of postoperative atrial fibrillation (POAF) in patients who have undergone coronary artery bypass grafting (CABG). The study will compare two cohorts: patients who developed POAF and those who did not (non-POAF), with the aim of improving postoperative care, reducing complications, and refining patient risk stratification.
Detailed description
Demographics (age, sex, ethnicity), lifestyle factors (smoking, alcohol, physical activity), and medical history (diabetes, hypertension, prior heart diseases) will be recorded. Surgical procedure details (number of grafts, use of intraoperative devices), anesthesia, and medications administered. Levels of inflammatory markers, cardiac-specific markers, and other relevant biomarkers at baseline and postoperatively. Other complications besides POAF, hospital length of stay, ICU admission, readmission rate, and mortality will also be monitored.
Interventions
All participants in the study will undergo the standard procedure of CABG. Continuous electrocardiogram monitoring and electrocardiography were used to identify the cardiac rhythm.
Sponsors
Study design
Eligibility
Inclusion criteria
* Adults aged 18 years or older. * Patients who underwent CABG.
Exclusion criteria
* Patients with a history of preoperative atrial fibrillation or other significant arrhythmias. * Patients who underwent other concurrent cardiac procedures (e.g., valve surgery) in addition to CABG. * Patients who cannot provide informed consent or lack adequate follow-up information.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of POAF | During hospital stay, up to 30 days | This will be determined based on electrocardiograms (ECG) and/or relevant medical records, within 30 days post-CABG. |
Secondary
| Measure | Time frame |
|---|---|
| Hospital length of stay | During hospital stay, up to 30 days |
| ICU admission time | During hospital stay, up to 30 days |
| Number of participants with Stroke | During hospital stay, up to 30 days |
| Mortality | During hospital stay, up to 30 days |
Countries
China