Focus Health Pregancy Women
Conditions
Brief summary
The study is aim to establish 95th and 99th percentile for healthy pregancy women for antiphospholipid antibodies(aPLs), such as aCL IgG/M/A, B2GP1 IgG/M/A, aPS/PT IgG/M. The outcome of the study is expected to aid Antiphospholipid syndrome patients diagnosis and managment. We also include some obstetirc Antiphospholipid syndrome(APS) patients to analysis the correlation between antiphospholipid antibodies and pregancy outcome, also want to know the prevalenc of aPLs, which can be guide for clinical application for APS diagnosis and treatment.
Interventions
DIAGNOSTIC_TESTDraw blood
Draw blood from human body and make into serum to test
Sponsors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* 120 non-pregnant healthy women, Age 18-45, with at least 1 successful pregnancy , no history of adverse pregnancy outcome, no abortion, still birth, premature delivery, preeclampsia * 120 pregnant women, Age 18-45, follow through the pregnancy and successful delivery without any adverse pregnancy outcome during the pregnancy process, no abortion, still birth, premature delivery, preeclampsia, no drug treatment * 60 APS pregnant patients diagnosed by clinical department
Exclusion criteria
1. Thrombosis history 2. Rheumatic immune disease 3. Use oral contraception or biological inhibitors 4. History of abortion, adverse pregnancy outcome, common high blood pressure, diabetes
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 95th and 99th pencentile data of pregancy and non-pregancy women | Oct. 2023 | 95th and 99th pencentile data of pregancy and non-pregancy women, and the prevalence of aPLs |
Contacts
Primary ContactHui Chen
Outcome results
None listed