Acute Ischemic Stroke
Conditions
Keywords
Acute ischemic stroke, Cerebral microbleeds, Influencing factors, Gender heterogeneity
Brief summary
The investigators continuously collected data from 482 AIS inpatients at the Neurology Department of Hebei General Hospital. Both demographic and clinical data were collected from the study subjects. Different head magnetic resonance imaging sequences were used to assess the subjects' CMBs, white matter lesions, and old lacunar infarcts (LI). Various statistical methods, including the t-test, χ2 test, and logistic regression, were used to analyze the gender heterogeneity of the influencing factors for CMBs in AIS patients.
Interventions
OTHERcerebral microbleeds
Whether patients with acute ischemic stroke are complicated by cerebral microbleeds
Sponsors
Xin Guo
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Aged 18 years and older * Must meet the diagnostic criteria for AIS as presented in the Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2014 * Must be in good physical condition and have the ability to cooperate with MRI examinations * Must have underwent SWI
Exclusion criteria
* MRI contraindications present, such as cardiac pacemaker, cardiac stents, or metal implants * Head MRI or carotid artery ultrasound suggests the presence of severe stenosis or occlusion in the intracranial or extracranial segments of the cerebral arteries * Severe comorbid diseases, such as cardiac, pulmonary, hepatic, and renal insufficiencies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of clinical data between AIS patients in CMB and non-CMB groups | from January 2014 to December 2015 | Differences in general information between AIS patients in CMB and non-CMB groups |
| Comparison of clinical data between male and female AIS patients | from January 2014 to December 2015 | Differences in general informationbetween male and female AIS patients |
| Comparison of CMB-related characteristics between the male and female AIS patients | from January 2014 to December 2015 | Differences in CMB-related characteristics between the male and female AIS patients |
| Predictive factor analysis for CMBs in male AIS patients | from January 2014 to December 2015 | CMB-related factors in male AIS patients |
| Predictive factor analysis for CMBs in female AIS patients | from January 2014 to December 2015 | CMB-related factors in female AIS patients |
Outcome results
None listed