Infectoius Keratitis
Conditions
Brief summary
The primary aim of this study is to investigate the efficiency of PACK\_ CXL in treatment of infectious keratitis and analyze postoperative outcomes.
Interventions
DRUGRiboflavin
topical application of riboflavin followed by cross linking
DRUGAntibotice.g vigamox ED Antifungal e.g Dflucan
topical application of antimicropial therapy
DEVICEpack cross linking
TOPICAL application of cross linking after application of Riboflavin TO TREAT INFECTIOUS KERATITIS
Sponsors
Sohag University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* are age ≥18 years, fungal, bacterial or mixed infectious keratitis, ulcer ≤ 4 mm in diameter and showing a maximum depth of 350 μm (as assessed by either optical coherence tomography (OCT))
Exclusion criteria
* age ≤18 years, viral infectious keratitis, non-infectiouskeratitis, melting corneal ulcers with impending perforation, corneal thickness \< 400 μm (including the corneal epithelium) and systemic diseases or systemic surgery, single-eyed and immunosuppressed patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| corneal THICKNESS | within 60 days | decrease corneal THICKNESS USING ANTERIOR SEGMENT OPTICAL COHERENT TOPOGRAPHY |
Countries
Egypt
Contacts
Primary Contactmariam A mohamed, assistant lecteure
Backup Contactmohamed i hafez, professor
Outcome results
None listed