Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05880797

Enrollment

1000

Registered

2023-05-30

Start date

2023-07-07

Completion date

2027-08-01

Last updated

2026-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human Papilloma Virus, Oropharyngeal Carcinoma

Brief summary

The purpose of this study is to better understand the natural history of oropharyngeal carcinoma (OPC), with or without an association with the human papilloma virus (HPV). For this study, the investigators plan to collect blood from OPC patients prior to treatment and at six subsequent time points.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients diagnosed with oropharyngeal carcinoma or patients with cancer of the unknown primary that is HPV associated, or possibly deemed to be originating from the oropharynx.

Exclusion criteria

* Not willing to sign consent

Design outcomes

Primary

Measure	Time frame	Description
Sample collection	prior to start of treatment	30-50cc of blood

Secondary

Measure	Time frame	Description
tumor sample	Day 1	tumor sample (FFPE) or fresh tissue post-excision or surgery, this will only be collected, if and when feasible, after the tumor has been removed post procedure.

Countries

United States

Contacts

CONTACTNikita Bedi

nbedi@stanford.edu(650) 723-5957

PRINCIPAL_INVESTIGATORChris Holsinger, MD

Stanford University

Outcome results