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Development and Validation of a Risk Prediction Model for Preoperative Frailty in Elderly Patients With Colorectal Cancer

Development and Validation of a Risk Prediction Model for Preoperative Frailty in Elderly Patients With Colorectal Cancer

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05879861
Enrollment
364
Registered
2023-05-30
Start date
2022-08-01
Completion date
2025-07-31
Last updated
2023-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer

Brief summary

Fried Scale and its related scales were used to analyze the status and risk factors of preoperative frailty in elderly patients with colorectal cancer. R software was used to construct a risk prediction model for preoperative frailty in elderly patients with colorectal cancer, and its validity and stability were verified in clinical practice.

Interventions

None listed

Sponsors

Zunyi Medical College
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
60 Years to No maximum

Inclusion criteria

1. patients who met the diagnostic criteria of colorectal cancer in Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer 2020 Edition and underwent surgery; 2. patients aged ≥60 years old ; 3. patients who are clearly conscious, able to understand instructions, communicate normally, and complete the physical activity ability test without the assistance of others; 4. patients who gave informed consent and volunteered to participate in the study.

Exclusion criteria

1. patients with limb joint disease and lower limb pain; 2. patients with serious heart, liver, kidney diseases could not complete the test; 3. patients with visual impairment and hearing impairment; 4. patients with a history of mental illness or drug dependence; 5. taking antidepressants, levodopa/carbidopa, donepezil hydrochloride and other drugs ; 6. patients who received preoperative radiotherapy and chemotherapy; 7. Patients with hypothyroidism, Parkinson's disease, stroke and other diseases.

Design outcomes

Primary

MeasureTime frameDescription
Status of frailty1 dayStatus of frailty will be assessed by Fried Scale

Countries

China

Contacts

Primary ContactYongmei Zhang
hulizym@yeah.net13885257269

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026