Postprandial Hyperglycemia
Conditions
Brief summary
the goal of this Randomized controlled cross over trial is to compare the effects of meal sequences VPF meal vs. SMM on the incremental area under the curve of postprandial glucose response among healthy adults in the UAE. the main question it aims to answer is what is the effect of meal sequence of vegetable and protein first followed by carbohydrates (VPF) compared to a standard mixed meal (SMM) on the postprandial glucose level and insulin response among healthy adults in the UAE. Participants will consume two is caloric test meals in random order (SMM and VPF meal sequences) separated by a 7-10-day washout period then blood sample will be collected at fasting ,30min,60min and 120mon for glucose and insulin and hunger ration will be done as well .Researchers will compare the effect of the two meals on postprandial blood glucose, insuline and hunger rating.
Interventions
OTHERvegetable and protein first followed by carbohydrates (VPF) meal sequence
vegetable and protein first followed10 min later by carbohydrates (VPF) meal sequence
Sponsors
University of Sharjah
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 59 Years
Healthy volunteers
Yes
Inclusion criteria
* The inclusion criteria were age of 18-59 years * Emirati, Gulf Cooperation Council (GCC), and Arabs ethnicity * BMI: 18.5-29.9 kg/m2 * Fasting blood glucose level less than 100 mg/dL * Non-smoker * no genetic or metabolic diseases * no known medical condition.
Exclusion criteria
* any participants with pre-existing diabetes * Pregnant and breastfeeding women * Participants with behaviors or/and health conditions that are known to affect glucose or -- insulin concentrations, such as smoking, gastrointestinal conditions, bariatric surgery, gastroparesis and reactive hypoglycemia * Participants who consumed medication that might affect glucose or insulin response * Participants with reported allergy or intolerance to any of the meal components (White Basmati rice, grilled chicken, cucumber, tomato, and lettuce salad with lemon olive oil dressing).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To compare the effects of meal sequences VPF meal vs. SMM on the incremental area under the curve of postprandial glucose response among healthy adults in the UAE. | 7-10 days | incremental area under the curve |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| To compare the effects of the VPF meal sequence vs. SMM sequence on the incremental area under the curve of postprandial insulin response. | 2 month | incremental area under the curve |
| To compare the postprandial hunger response of the VPF meal sequence vs SMM sequence on the area under the curve using a validated visual analog scale for hunger and fullness (VAS) | 7-10 days | \]area under the curve |
Countries
United Arab Emirates
Outcome results
None listed