COVID-19, Barotrauma
Conditions
Brief summary
During the pandemic of COVID-19, studies reporting a high incidence of barotrauma, both pneumothorax but also pneumomediastinum, in patients with critical COVID-19. If this is complications of the respiratory support used to treat patients hypoxemia or if it is a direct consequence of COVID-19 damaging the lung tissue is not known. The aim of this study is to investigate the incidence and type barotrauma, if there is an association between barotrauma and level of respiratory support used in the intensive care unit, and if barotrauma is associated with worse outcome compared to patients without barotrauma.
Interventions
PROCEDUREOpen system
Oxygen delivered on open system, for example high flow nasal cannula or low flow oxygen by nasal cannula or face mask
PROCEDURENon-invasive mechanical ventilation
Respiratory support by for example continues or bilevel positive airway pressure
PROCEDUREInvasive mechanical ventilation
Respiratory support delivered through endotracheal tube or tracheostomy
Sponsors
Karolinska Institutet
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Positive polymerase chain reaction for SARS-CoV-2 * Admitted to ICU due to respiratory failure
Exclusion criteria
* Transferred to or from an ICU in other hospital/region making data collection regarding baseline data/outcomes not possible
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Barotrauma | 28 days from ICU admission | Pneumothorax, pneumomediastinum, pneumatocele or subcutaneous emphysema as verified by radiology |
Countries
Sweden
Outcome results
None listed