Healthy
Conditions
Keywords
blood pressure, cold pressor test, heart rate
Brief summary
The purpose of this study is to evaluate the effects of left nostril breathing in young females having cardiovascular hyper reactivity to cold pressor test.Although,limited literature exist regarding hyper reactivity towards stress induced test in our youth and its effective and easy treatment in the form of left nostril breathing which could proves to be beneficial for our youth.
Detailed description
The Cold Pressor Test (CPT) was introduced as a standard incentive for studying the vasomotor response (Hines and Brown 1932). Hyper-reactors were the subjects in his study who responded more strongly to CPT, Participants who show hyper reactivity to Cold pressor test (i.e. subjects showing 25 mmHg increase in systolic blood pressure along with 20 mmHg increase in diastolic blood pressure).They proposed that these hyper reactive could be candidates for hypertension in the future. Increased occurrence of these diseases could be attributed to an asymmetry in sympathetic and parasympathetic stimulation. Control or adaptation of breathing or breathing workouts i-e yoga are thought to be beneficial in the treatment of such disease. Although Yoga techniques proven to be effective in treating stress related disorders but it is time consuming and young population because of their busy routine couldn't be able to take out time for their health related issues. This study introduces very simple exercise in the form of left nostril breathing which decreases sympathetic activity and increases parasympathetic activity. It is inversely proportional to stress induced response of the body, it is very easy to perform and can be done at any time, and if found significantly effective for stress disorder ,it could be used in daily routine by our youth to get themselves prevented from major risk factors of CVD's particularly hypertension. This study will identify participants with a high potential risk of developing hypertension in the future by administering Cold pressor test, additionally the effects of left nostril breathing intervention on hyper reactive participants would be observed and if found significant, it would be a major breakthrough in primary prevention of hypertension.
Interventions
OTHERLeft Nostril Breathing
The participants which will show cardiovascular hyper reactivity towards CPT will be divided into 2 groups having 30 participants in each group. Experimental group will receive Left Nostril Breathing(slow, deep breath taken through your left nostril while closing your right nostril with your right thumb. Then just as gently exhale long, slowly, and completely through the left nostril, just as gently. It will be done while sitting) for 10 minutes twice a day for the duration of 12 weeks. Follow up will be taken through administration Cold pressor test after every 4,8 and 12 weeks.
OTHERConventional
30 participants will be recruited in conventional group which will receive simple deep breathing exercises of 3 sessions per week for the duration of 12 weeks.Follow up will be taken after every 4,8 and 12 weeks.
Sponsors
Riphah International University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 25 Years
Healthy volunteers
No
Inclusion criteria
* Participants falling in the following category would be recruited into the study: * Females Age (18-25) years * Participants who show hyper reactivity to Cold pressor test (i.e subjects showing 25mmHg increase in systolic blood pressure along with 20mmHg increase in diastolic blood pressure) * Consenting participants.
Exclusion criteria
* The participants in the following category would be excluded from the study: * Participants on antihypertensive drugs. * Participants who are diagnosed with any cardiovascular, renal, hepatic or metabolic disease. * Participants having malignant tumor. * Participants with nasal blockages, polyps ,Raynaud phenomena * Females during menstrual cycle, pregnancy or on oral contraceptives.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Heart Rate | After 4 weeks | Pulse oximeter will be applied to the participant to measure their Heart rate. |
| Cold pressor test | After 4 weeks | Cold pressor test will be conducted on participants to measure cardio vascular hyper reactivity to stress induce test. |
| Blood pressure | After 4 weeks | Mercury sphygmomanometer will be used to measure blood pressure of participants |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen saturation | after 4 weeks | Pulse oximeter will be used on participant to measure Spo2. |
Countries
Pakistan
Outcome results
None listed