Attention Deficit Disorder With Hyperactivity
Conditions
Keywords
Sleep, Memory
Brief summary
Attention Deficit Disorder With Hyperactivity is associated with deficits in cognition and sleep. In healthy adults, memory consolidation processes are related to sleep spindle activity in the sleep electroencephalogram. This association is poorly characterized in adults with attention deficit hyperactivity. In this study, the purpose is to characterize sleep microarchitecture disorders through the analysis of different stage of sleep EEG activity during a polysomnographic examination in adult with mixed Attention Deficit Disorder With Hyperactivity presentation compared to healthy.
Interventions
Neurological, neuropsychological, polysomnography examinations and multiple sleep latency test. The protocol is divided into three visits.
Sponsors
University Hospital, Toulouse
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
for all participants: * Age from 18 to 45 years old * Affiliated to the French health care system Inclusion Criteria for attention deficit hyperactivity disorder patients: * meeting Diagnostic and Statistical Manual (DSM)-5 criteria for mixed attention deficit hyperactivity disorder presentation without drug treatment for attention deficit hyperactivity disorder.
Exclusion criteria
for all participant: * People not able to give consent, neurological disease (other than neurodevelopmental disorders; or any other serious disease (cancer, addiction, systemic disease)), untreated sleep apnea, major depression (Beck inventory \> 15), untreated restless leg syndrome; pregnancy in progress or wish to become pregnant during the study or breastfeeding woman, drug treatment including benzodiazepine, neuroleptic or antidepressant before inclusion.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference in signal power (db or μV 2) in the sigma frequency bands in N2 sleep | 1 day | difference between 2 groups |
Contacts
Primary ContactMélanie PLANTON, PhD
Outcome results
None listed