Articulatory Adaptation Following Oral Cancer Treatment

Speech Flexibility in Adulthood Following Oral Cancer Treatment: Acoustic and Kinematic Explorations

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05876247

Acronym

SPOKE

Enrollment

Registered

2023-05-25

Start date

2022-11-10

Completion date

2025-08-31

Last updated

2023-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Cavity Squamous Cell Carcinoma, Speech Disorders

Keywords

Articulation

Brief summary

The goal of this longitudinal study is to learn more about the articulatory consequences of surgical oral cancer treatment. The main aims are to study the coordination and development of speech articulation of patients who will undergo surgical treatment for oral cancer longitudinally and whether individual differences in the reliance on auditory or tactile information can predict the success of speech compensatory strategies. Participants will perform multiple speech tasks while motion tracking sensors track the articulatory gestures.

Interventions

OTHERElectromagnetic Articulography

Motion tracking sensors will track articulatory movements of the tongue, jaw and lips

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Diagnosed with T1 or T2 tumor in the oral cavity 2. At least 18 years old and able to provide informed consent 3. Native speaker of Dutch 4. Has nog been treated for oral cancer before

Exclusion criteria

1a. Recurrence of disease (for patients) 1b. Treated for oral cancer (for healthy controls) 2. Speech problems (e.g., stuttering) 3. Problems with sight or hearing that impede reading or understanding instructions. When glasses or a hearing aid resolve these problems, then participants are not excluded. 4\. Neurological or psychological disorders (e.g., stroke) 5. Non-removable metal in, on or around the head (piercings, braces, pacemaker, electrodes) 6. Self-reported signs of depression

Design outcomes

Primary

Measure	Time frame	Description
Articulatory gestures	2022-2025	Articulatory movements in three dimensions of the tongue, lips and jaw as measured by the NDI Vox Electromagnetic Articulograph. Measures include: articulator speed (mm/s), total displacement (mm), coordinates (x,y,z) during specific gestures.
Acoustic outcomes	2022-2025	Speech acoustics will be measured in Praat and include the first and second formants of vowels (in Hz), global movement size in terms of acoustic working space (Hz-squared), and the centre of gravity of sibilants (in Hz)

Countries

Netherlands

Contacts

Primary ContactThomas Tienkamp, MA

t.b.tienkamp@umcg.nl+31 50 36 37051

Backup ContactMax Witjes, PhD

m.j.h.witjes@umcg.nl+31 (0)50 361 3841

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026