Cleft Lip and Palate
Conditions
Keywords
Orthognathic Surgery, Cleft Lip and Palate
Brief summary
In a prospective longitudinal study design, details in jaw-neck kinematics and electromyography (EMG) activity changes in patients (women and men) referred for surgical correction of basal relations between the maxilla and mandible over time; pre-operative and during follow-up 8 weeks and 18 months after surgical correction will be evaluated. The results will contribute with novel insights on jaw-neck motor function before, in short- and long-term after the surgical process. We will have blinded evaluation of outcomes.
Detailed description
Consecutive patients referred to department of Oral and Maxillofacial Surgery, Umeå University Hospital for corrective maxillofacial-mandibular surgery, will offer opportunity to be included in the study. Expected number of patients: 20 - 25 patients annually. Blinded evaluation will be pre-operative and during follow-up 8 weeks and 18 months after surgical correction.
Interventions
PROCEDUREOrthognathic surgery
Surgical corrections of the maxilla and/or the mandible. Integrated jaw-neck movement patterns, muscle activity, bite force and occlusal contact area will be registered and mapped with quantitative objective functional variables. The state-of-the-art core equipment to evaluate jaw-neck motor function in detail is located in the Movement Lab (Department of Odontology, Umeå University).
Sponsors
Umeå University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
16 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
s: * Patients accepted for orthognathic surgery due to jaw discrepancies. * Patients given their consent for participation
Exclusion criteria
s: * Patients with syndromes * Patients not given their consent for participation * Patients unable to follow instructions due to lack of knowledge in Swedish and/or English language
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Kinematic outcome variables | Preoperatively, postoperatively 8 weeks, 18 months | Jaw and head movement amplitudes (mm) |
| Change in Electromyography (EMG) | Preoperatively, postoperatively 8 weeks, 18 months | Muscle activity in micro-Volt in jaw and neck muscles bilaterally |
| Change in Maximum voluntary occlusal bite force (MVOBF) | Preoperatively, postoperatively 8 weeks, 18 months | Newton (N) |
| Change in Occlusal contact area | Preoperatively, postoperatively 8 weeks, 18 months | mm2 |
Countries
Sweden
Outcome results
None listed