Aged, Deprescriptions, Inappropriate Prescribing, Polypharmacy, Potentially Inappropriate Medications
Conditions
Brief summary
The goal of this randomized controlled trial is to assess the effectiveness of a pharmacist-led medication review using the locally developed Malaysian Potentially Inappropriate Prescribing Screening tool in Older Adults (MALPIP), an explicit criteria in hospitalized older adults. The main questions it aims to answer are: 1. The effectiveness of the intervention in reducing the number of PIMs and chronic medications after discharge 2. The impact of the intervention on quality of life, falls events, emergency department visits, readmissions and survivals Researchers will compare the control group to see if there is corresponding changes to the outcomes specified above.
Interventions
OTHERMALPIP criteria
In the intervention group, the clinical pharmacist will apply the MALPIP criteria on all the admission and discharge medications. The intervention will consist of 4 steps: i) pharmacist review using MALPIP criteria to detect PIM, ii) discussion with doctors for deprescribing decision iii) discussion with patients and documentation of shared decision iv) follow up patients
Sponsors
Hospital Raja Permaisuri Bainun
Monash University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 60 years and above * Taking more than five regular drugs * Having at least one chronic medical condition * Ability to understand and speak Malay, English, or Mandarin language
Exclusion criteria
* Admitted for end-of-life care * Diagnosed with terminal illness * Diagnosed with active cancer * Participated in another drug trial * Refused or unable to give consent * Visited the Emergency Department without admission to ward * Readmitted and have been previously enrolled in the trial
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of potentially inappropriate medications | Admission up to 18 months |
| Number of chronic medications | Admission up to 18 months |
Countries
Malaysia
Outcome results
None listed