Skip to content

Myocardial Function Assessment in Patients With Coronary Artery Disease Using Noninvasive Myocardial Work

Myocardial Function Assessment in Patients With Coronary Artery Disease Using Noninvasive Myocardial Work

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05874752
Enrollment
130
Registered
2023-05-25
Start date
2021-10-01
Completion date
2023-06-01
Last updated
2023-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease, Noninvasive Myocardial Work

Brief summary

Noninvasive pressure-strain loop (PSL) derived myocardial work (MW) are more sensitive than conventional echocardiographic parameters in quantitative assessment of early myocardial dysfunction. The aim of this study was to assess left ventricular (LV) myocardial function in symptomatic patients with coronary artery disease using the promising method. Methods: Transthoracic echocardiography was performed on patients with angina or equivalent symptoms before coronary angiography. Images were stored and imported into the software for further offline analysis of PSL-based MW. MW analysis were carried out on each patient for global and regional myocardial function assessment.

Interventions

DIAGNOSTIC_TESTTransthoracic echocardiography

noninvasive myocardial work

Sponsors

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

Patients who were hospitalized for coronary angiography with angina or equivalent symptoms. \-

Exclusion criteria

Acute coronary syndrome, left main stem coronary disease, left ventricular ejection fraction (LVEF) below 55%, observed resting regional wall motion abnormalities (RWMAs), non-sinus rhythm, intraventricular block, previous cardiac surgery, severe valvular heart disease, hypertrophic cardiomyopathy, myocarditis, pericardial diseases, pulmonary hypertension, and poor image quality. \-

Design outcomes

Primary

MeasureTime frameDescription
myocardial functionbaseline (before coronary angiography)noninvasive myocardial work indices

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026