Type 2 Diabetes
Conditions
Brief summary
Type 2 diabetes mellitus (DM) has adopted a top priority as it is a disease with an increasing prevalence. The number of people living with DM has increased more than fourfold over the past 40 years to more than 460 million people today
Detailed description
All-cause mortality rates have declined substantially in several high-income countries, including England. A diversification in non-fatal conditions in people with DM has also been reported. This is attributable to broader, non-vascular conditions. Due to increasing longevity among people with type 2 DM with increasing and diversifying multimorbidity in them, the health needs of people with Type 2 DM are therefore likely to be broad, and complex. Finding multimorbidity (two or more chronic conditions) is common in people with Type 2 DM and increasing, but the comorbidity profiles of people with T2DM vary substantially. Many studies have primarily focused on identifying multimorbidity patterns in the general population. The understanding of multimorbidity patterns and composition of specific comorbidities in people with DM, and how this varies across patient groups and during the course of the disease, is limited. Further knowledge of this could provide insight into providing more holistic and more personal approaches to clinical guideline development, care pathways, and secondary prevention.
Interventions
DIAGNOSTIC_TESTHBA1C
blood sample on EDTA
DIAGNOSTIC_TESTLipid profile, including total, LDL, and HDL cholesterol and Triglycerides
serum sample
DIAGNOSTIC_TESTUrine analysis and urinary albumin-to-creatinine ratio
Morning urine sample
DIAGNOSTIC_TESTSerum creatinine and estimated glomerular filtration rate
serum sample
DIAGNOSTIC_TESTComplete blood count
blood sample on EDTA
DIAGNOSTIC_TESTThyroid-stimulating hormone
serum sample
DIAGNOSTIC_TESTSerum iron, TIBC, Transferrin saturation and serum ferritin if needed
serum sample
PROCEDUREElectrocardiography (ECG)
by electrocardiogram
PROCEDURETransthoracic echocardiography, Neck ultrasonography if needed and abdominopelvic ultrasound
imaging
PROCEDUREArterial duplex ultrasound of both lower limbs
imaging
DIAGNOSTIC_TESTRandom blood glucose
serum sample
DIAGNOSTIC_TESTAST, ALT, albumin
serum sample
Sponsors
New Valley University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Patients with type 2 diabetes.
Exclusion criteria
1. Patients with type 1 diabetes. 2. Patients with secondary diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of participants with Coronary heart disease | At time of inclusion in the study |
| Number of participants with dyslipidemia | At time of inclusion in the study |
| Number of participants with Diabetic kidney disease | At time of inclusion in the study |
| Number of participants with Peripheral neuropathy | At time of inclusion in the study |
| Number of participants with Liver disease | At time of inclusion in the study |
| Number of participants with Infections | At time of inclusion in the study |
| Number of participants with Cancer | At time of inclusion in the study |
| Number of participants with thyroid disorder | At time of inclusion in the study |
| Number of participants with Stroke | At time of inclusion in the study |
| Number of participants with Peripheral arterial disease | At time of inclusion in the study |
| Number of participants with Diabetic eye disease | At time of inclusion in the study |
| Number of participants with hypertension | At time of inclusion in the study |
Secondary
| Measure | Time frame |
|---|---|
| Correlate the presence of each co-morbidity with the extent of diabetes control | At time of inclusion in the study |
| Number of participants with controlled diabetes mellitus with correlation to the number of cormobidity | At time of inclusion in the study |
Countries
Egypt
Contacts
Primary ContactAsmaa N Hussein, MD
Outcome results
None listed