Cardiomyopathies
Conditions
Brief summary
Cardiomyopathy is the most common inherited cardiovascular disease, showing family aggregation, so it has a huge psychological and economic burden on family members. Studying the clinical characteristics of patients with cardiomyopathy is helpful for further diagnosis, treatment and management, which has important clinical and social significance.
Detailed description
In this study, patients hospitalized with cardiomyopathy as the primary discharge diagnosis in China are recruited prospectively after informed consent was given. The investigator will collect the baseline clinical characteristics of the patients at enrollment, including comprehensive physical examination, laboratory testing of blood and urine, electrocardiography, 24-hour Holter, echocardiography, MRI and other examinations if necessary. Data are collected with the use of case report forms (CRFs) and are entered into a web-based system. A 6 mL venous blood sample is obtained from consenting patients. Each participant is scheduled to be followed up by telephone every 12 months after admission to hospital.
Interventions
None listed
Sponsors
China National Center for Cardiovascular Diseases
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients with primary discharge diagnosis meeting one of the following subtypes of cardiomyopathy were enrolled, including HCM, DCM, ACM, RCM, left ventricular non-compaction, cardiac amyloidosis, Fabry disease, Pompe disease, Danon disease, and PRKAG2 cardiac syndrome.
Exclusion criteria
* Patients who refuse to sign the informed consent or decline follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of participants with cardiovascular deaths | an average of 1 year | including sudden cardiac death and deaths due to heart failure and stroke |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| number of participants with heart failure | an average of 1 year | progress to level III or IV in New York Heart Association class |
| number of participants with stroke | an average of 1 year | including cerebral infraction and hemorrhage |
| number of participants with myocardial infarction | an average of 1 year | including ST-segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction |
| number of participants with all-cause deaths | an average of 1 year | including deaths due to any causes |
Countries
China
Contacts
Primary ContactLei Song, MD.&phD
Outcome results
None listed