White Spot Lesion of Tooth
Conditions
Keywords
white spot lesion, diode laser, vita easy shade V
Brief summary
Dental caries is a very common condition, and although it has become less common, it still represents a serious public health risk. Caries symptoms range from the earliest molecular alterations in the tooth's apatite crystals to an apparent white spot lesion (WSL) or eventual cavitation. The white spot lesion looks chalky because minerals are being lost from both the surface and the underside of the enamel. A relatively simple and noninvasive caries preventive regimen in treating white spot lesions with low-level laser irradiation, either alone or with topical fluoride treatment. This treatment results in reduced enamel solubility and dissolution.
Detailed description
The study was reviewed and approved by the Ethical research committee of the Faculty of Dental Medicine for Girls; at Al-Azhar University, Cairo, Egypt. This study was conducted on 90 teeth with white spot lesions (WSLs) detected clinically on the buccal surface of teeth. The patients with WSLs were selected randomly from the operative dentistry clinic at the Faculty of Dentistry, Girl's Branch, Al-Azhar University After examination, the teeth will be assigned into six groups of 15 teeth with white spot lesions each according to the remineralizing material used: * The first group (A1B1): The teeth with WSL will be treated with nano-hydroxyapatite +fluoride with laser application. * The second group (A1B2): The contralateral teeth will be treated with nano-hydroxyapatite +fluoride without laser application. * The third group (A2B1): The teeth with WSL will be treated with nano-hydroxyapatite + xylitol with laser application. * The fourth group (A2B2): The contralateral teeth will be treated with nano hydroxyapatite+ xylitol without laser application. * The fifth group (A3B1): The teeth with WSL will be treated with 5% sodium fluoride varnish with laser application. * The sixth group (A3B2): The contralateral teeth will be treated with 5% sodium fluoride without laser application.
Interventions
PROCEDURERemin Pro
A photosensitizing-remineralizing agent mixture was prepared by adding pre-green dye The diode laser was irradiated immediately with 1 W, Exposure time of 10 s, 810 nm, continuous and non-contact mode.
PROCEDUREX Pur Remin
A photosensitizing-remineralizing agent mixture was prepared by adding pre-green dye The diode laser was irradiated immediately with 1 W, Exposure time of 10 s, 810 nm, continuous and non-contact mode.
PROCEDUREFluoride varnish
A photosensitizing-remineralizing agent mixture was prepared by adding pre-green dye The diode laser was irradiated immediately with 1 W, Exposure time of 10 s, 810 nm, continuous and non-contact mode.
Sponsors
Al-Azhar University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Masking description
To avoid bias and for proper randomization, the study will be done per patient using tossing a coin to assign the tooth to be either treated with Nano hydroxyapatite with fluoride or Nano hydroxyapatite with xylitol or sodium fluoride.
Intervention model description
* The first group (A1B1):15 teeth with WSL were treated with Remin Pro with laser application. * The second group (A1B2): The contralateral 15 teeth were treated with Remin Pro without laser application. The third group (A2B1): 15 teeth with WSL were treated with X Pur Remin with laser application. * The fourth group (A2B2): The contralateral 15 teeth will be treated with XPur Remin without laser application. * The fifth group (A3B1): 15 teeth with WSL were treated with 5% sodium fluoride varnish with laser application. * The sixth group (A3B2): The contralateral 15 teeth were treated with 5% sodium fluoride without laser application
Eligibility
Sex/Gender
FEMALE
Age
15 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* The patients should be 13-40 years old. * Patients should have good oral hygiene. * The patients with good general health and no systemic disease.
Exclusion criteria
* \- Presence of enamel hypoplasia or dental fluorosis. * Presence of carious cavity. * Patients who have a significant medical history, * Patients who have evidence of reduced salivary flow or significant tooth wear.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Spectrophotometric color assessment: | from base line (application of materials) to one month | The Vita Easy shade spectrophotometer (Vita Zahnfabrik, Bad Säckingen, Germany) was employed for the color assessment WSLs |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| surface area measurement | from base line (application of materials) to one month | after the finalization of the remineralization protocol, another radiographic examination was undertaken. Bitewing radiographs of the lesions were taken using the same X-ray unit, film holders for bite recording and vertical angulations for standardizing the geometric projection of the X-ray beam by digital subtraction radiograph. |
Countries
Egypt
Outcome results
None listed